Gentianella turkestanerum Showed Protective Effects on Hepatic Injury by Modulating the Endoplasmic Reticulum Stress and NF-&#954;B Signaling Pathway.

Yang, Jianhua; Zhu, Dandan; Wen, Limei; Xiang, Xueying; Hu, Junping

Gentianella turkestanerum Showed Protective Effects on Hepatic Injury by Modulating the Endoplasmic Reticulum Stress and NF-κB Signaling Pathway.

Yang, Jianhua; Zhu, Dandan; Wen, Limei; Xiang, Xueying; Hu, Junping.

Affiliation

Yang J; Department of Pharmacy, The First Affiliated Hospital, Xinjiang Medical University, Urumqi 830011, China.
Zhu D; Department of Pharmacy, The First Affiliated Hospital, Xinjiang Medical University, Urumqi 830011, China.
Wen L; Department of Pharmacy, The First Affiliated Hospital, Xinjiang Medical University, Urumqi 830011, China.
Xiang X; College of Pharmacy, Xinjiang Medical University, Urumqi 830011, China.
Hu J; College of Pharmacy, Xinjiang Medical University, Urumqi 830011, China.

Curr Mol Med ; 19(6): 452-460, 2019.

Article in En | MEDLINE | ID: mdl-30987565

Subject(s)

Endoplasmic Reticulum Stress/drug effects; Gentianella/chemistry; Hepatocytes/drug effects; Hepatocytes/metabolism; Plant Extracts/pharmacology; Protective Agents/pharmacology; Signal Transduction/drug effects; Apoptosis/drug effects; Biomarkers; Carbon Tetrachloride/adverse effects; Cell Line; Gene Expression Regulation/drug effects; Humans; Hydrogen Peroxide/pharmacology; Liver/drug effects; Liver/metabolism; Liver/pathology; Liver Function Tests; NF-kappa B/metabolism; Oxidation-Reduction/drug effects; Oxidative Stress/drug effects; Plant Extracts/chemistry; Protective Agents/chemistry

Key words

Gentianella turkestanerum; Hepatic L02 cell; butanol; carbon tetrachloride; hydrogen peroxide; liver injury.

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plant Extracts / Signal Transduction / Protective Agents / Hepatocytes / Gentianella / Endoplasmic Reticulum Stress Type of study: Prognostic_studies Limits: Humans Language: En Journal: Curr Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2019 Type: Article Affiliation country: China

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