Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells.
Sci Rep
; 9(1): 6136, 2019 04 16.
Article
in En
| MEDLINE
| ID: mdl-30992475
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Histone Deacetylase Inhibitors
/
Programmed Cell Death 1 Receptor
/
Histone Deacetylase 6
/
Antineoplastic Agents, Immunological
/
Macrophages
/
Neoplasms
Limits:
Animals
Language:
En
Journal:
Sci Rep
Year:
2019
Type:
Article
Affiliation country:
United States