Your browser doesn't support javascript.
loading
Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway.
Karki, Rajeshri G; Powers, James; Mainolfi, Nello; Anderson, Karen; Belanger, David B; Liu, Donglei; Ji, Nan; Jendza, Keith; Gelin, Christine F; Mac Sweeney, Aengus; Solovay, Catherine; Delgado, Omar; Crowley, Maura; Liao, Sha-Mei; Argikar, Upendra A; Flohr, Stefanie; La Bonte, Laura R; Lorthiois, Edwige L; Vulpetti, Anna; Brown, Ann; Long, Debby; Prentiss, Melissa; Gradoux, Nathalie; de Erkenez, Andrea; Cumin, Frederic; Adams, Christopher; Jaffee, Bruce; Mogi, Muneto.
Affiliation
  • Karki RG; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Powers J; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Mainolfi N; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Anderson K; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Belanger DB; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Liu D; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Ji N; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Jendza K; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Gelin CF; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Mac Sweeney A; Novartis Institutes for BioMedical Research , Novartis Campus , CH-4056 Basel , Switzerland.
  • Solovay C; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Delgado O; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Crowley M; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Liao SM; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Argikar UA; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Flohr S; Novartis Institutes for BioMedical Research , Novartis Campus , CH-4056 Basel , Switzerland.
  • La Bonte LR; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Lorthiois EL; Novartis Institutes for BioMedical Research , Novartis Campus , CH-4056 Basel , Switzerland.
  • Vulpetti A; Novartis Institutes for BioMedical Research , Novartis Campus , CH-4056 Basel , Switzerland.
  • Brown A; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Long D; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Prentiss M; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Gradoux N; Novartis Institutes for BioMedical Research , Novartis Campus , CH-4056 Basel , Switzerland.
  • de Erkenez A; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Cumin F; Novartis Institutes for BioMedical Research , Novartis Campus , CH-4056 Basel , Switzerland.
  • Adams C; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Jaffee B; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
  • Mogi M; Novartis Institutes for BioMedical Research , Cambridge , Massachusetts 02139 , United States.
J Med Chem ; 62(9): 4656-4668, 2019 05 09.
Article in En | MEDLINE | ID: mdl-30995036
Subject(s)
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzylamines / Serine Proteinase Inhibitors / Complement Pathway, Alternative Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2019 Type: Article Affiliation country: United States
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzylamines / Serine Proteinase Inhibitors / Complement Pathway, Alternative Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2019 Type: Article Affiliation country: United States