A Clinically Applicable Gene-Expression Classifier Reveals Intrinsic and Extrinsic Contributions to Consensus Molecular Subtypes in Primary and Metastatic Colon Cancer.

Piskol, Robert; Huw, Ling; Sergin, Ismail; Kljin, Christiaan; Modrusan, Zora; Kim, Doris; Kljavin, Noelyn; Tam, Rachel; Patel, Rajesh; Burton, Jeremy; Penuel, Elicia; Qu, Xueping; Koeppen, Hartmut; Sumiyoshi, Teiko; de Sauvage, Frederic; Lackner, Mark R; de Sousa E Melo, Felipe; Kabbarah, Omar

Piskol, Robert; Huw, Ling; Sergin, Ismail; Kljin, Christiaan; Modrusan, Zora; Kim, Doris; Kljavin, Noelyn; Tam, Rachel; Patel, Rajesh; Burton, Jeremy; Penuel, Elicia; Qu, Xueping; Koeppen, Hartmut; Sumiyoshi, Teiko; de Sauvage, Frederic; Lackner, Mark R; de Sousa E Melo, Felipe; Kabbarah, Omar.

Affiliation

Piskol R; Bioinformatics and Computational Biology, Genentech, Inc., South San Francisco, California. desousaf@gene.com omarkabbarah@gmail.com.
Huw L; Oncology Biomarker Development, Genentech, Inc., South San Francisco, California. desousaf@gene.com omarkabbarah@gmail.com.
Sergin I; Molecular Oncology, Genentech, Inc., South San Francisco, California.
Kljin C; Bioinformatics and Computational Biology, Genentech, Inc., South San Francisco, California.
Modrusan Z; Molecular Biology, Genentech, Inc., South San Francisco, California.
Kim D; Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.
Kljavin N; Molecular Oncology, Genentech, Inc., South San Francisco, California.
Tam R; Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.
Patel R; Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.
Burton J; Molecular Oncology, Genentech, Inc., South San Francisco, California.
Penuel E; Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.
Qu X; Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.
Koeppen H; Pathology, Genentech, Inc., South San Francisco, California.
Sumiyoshi T; Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.
de Sauvage F; Molecular Biology, Genentech, Inc., South San Francisco, California.
Lackner MR; Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.
de Sousa E Melo F; Discovery Oncology, Genentech, Inc., South San Francisco, California. desousaf@gene.com omarkabbarah@gmail.com.
Kabbarah O; Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.

Clin Cancer Res ; 25(14): 4431-4442, 2019 07 15.

Article in En | MEDLINE | ID: mdl-31004000

Subject(s)

Biomarkers, Tumor/genetics; Colorectal Neoplasms/classification; Colorectal Neoplasms/genetics; Gene Expression Profiling/methods; Gene Expression Regulation, Neoplastic; Molecular Typing/methods; Mutation; Animals; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cohort Studies; Colorectal Neoplasms/secondary; Female; Humans; Mice; Mice, Inbred NOD; Neoplasm Metastasis; Neoplasm Staging; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Biomarkers, Tumor / Gene Expression Regulation, Neoplastic / Gene Expression Profiling / Molecular Typing / Mutation Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2019 Type: Article

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