Protein kinase C-mediated insulin receptor phosphorylation in diabetic rat retina.

Kida, Teruyo; Oku, Hidehiro; Horie, Taeko; Osuka, Sho; Fukumoto, Masanori; Ikeda, Tsunehiko

Kida, Teruyo; Oku, Hidehiro; Horie, Taeko; Osuka, Sho; Fukumoto, Masanori; Ikeda, Tsunehiko.

Affiliation

Kida T; Department of Ophthalmology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, 569-8686, Japan. opt038@osaka-med.ac.jp.
Oku H; Department of Ophthalmology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, 569-8686, Japan.
Horie T; Department of Ophthalmology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, 569-8686, Japan.
Osuka S; Department of Ophthalmology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, 569-8686, Japan.
Fukumoto M; Department of Ophthalmology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, 569-8686, Japan.
Ikeda T; Department of Ophthalmology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, 569-8686, Japan.

Graefes Arch Clin Exp Ophthalmol ; 257(7): 1427-1434, 2019 Jul.

Article in En | MEDLINE | ID: mdl-31025213

Subject(s)

Diabetes Mellitus, Experimental; Diabetic Retinopathy/metabolism; Endothelium, Vascular/metabolism; Protein Kinase C/metabolism; Receptor, Insulin/metabolism; Retinal Vessels/metabolism; Animals; Blotting, Western; Cell Proliferation; Cells, Cultured; Diabetic Retinopathy/pathology; Endothelium, Vascular/pathology; Male; Phosphorylation; Photomicrography; Rats; Rats, Wistar; Retinal Vessels/pathology

Key words

Akt; Insulin receptor; PMA (phorbol myristate acetate); Pericyte; Retinal vascular endothelial cell

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retinal Vessels / Protein Kinase C / Receptor, Insulin / Endothelium, Vascular / Diabetes Mellitus, Experimental / Diabetic Retinopathy Limits: Animals Language: En Journal: Graefes Arch Clin Exp Ophthalmol Year: 2019 Type: Article Affiliation country: Japan

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