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A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action.
Yang, Jason H; Wright, Sarah N; Hamblin, Meagan; McCloskey, Douglas; Alcantar, Miguel A; Schrübbers, Lars; Lopatkin, Allison J; Satish, Sangeeta; Nili, Amir; Palsson, Bernhard O; Walker, Graham C; Collins, James J.
Affiliation
  • Yang JH; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Wright SN; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Hamblin M; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • McCloskey D; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2800 Lyngby, Denmark.
  • Alcantar MA; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Schrübbers L; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2800 Lyngby, Denmark.
  • Lopatkin AJ; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Wyss Institute for Biologically Inspired E
  • Satish S; Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
  • Nili A; Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
  • Palsson BO; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2800 Lyngby, Denmark; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA.
  • Walker GC; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Collins JJ; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Wyss Institute for Biologically Inspired E
Cell ; 177(6): 1649-1661.e9, 2019 05 30.
Article in En | MEDLINE | ID: mdl-31080069
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Metabolic Networks and Pathways / Anti-Bacterial Agents Language: En Journal: Cell Year: 2019 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Metabolic Networks and Pathways / Anti-Bacterial Agents Language: En Journal: Cell Year: 2019 Type: Article Affiliation country: United States