Optimized Cross-Linking Mass Spectrometry for in Situ Interaction Proteomics.

Ser, Zheng; Cifani, Paolo; Kentsis, Alex

Ser, Zheng; Cifani, Paolo; Kentsis, Alex.

Affiliation

Kentsis A; Department of Pediatrics, Pharmacology, and Physiology & Biophysics, Weill Cornell Medical College , Cornell University , New York , New York 10065 , United States.

J Proteome Res ; 18(6): 2545-2558, 2019 06 07.

Article in En | MEDLINE | ID: mdl-31083951

Subject(s)

Mass Spectrometry/methods; Peptides/genetics; Protein Interaction Maps/genetics; Proteomics/methods; Cross-Linking Reagents/chemistry; Humans; In Situ Hybridization; Peptides/chemistry; Peptides/isolation & purification; Protein Interaction Mapping

Key words

BSA; chromatin; cross-linking; database search; false positive discovery; mass spectrometry; protein−protein interactions; proteomics; target-decoy strategy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Mass Spectrometry / Proteomics / Protein Interaction Maps Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Proteome Res Journal subject: BIOQUIMICA Year: 2019 Type: Article

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