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Kappa chain maturation helps drive rapid development of an infant HIV-1 broadly neutralizing antibody lineage.
Simonich, Cassandra A; Doepker, Laura; Ralph, Duncan; Williams, James A; Dhar, Amrit; Yaffe, Zak; Gentles, Lauren; Small, Christopher T; Oliver, Brian; Vigdorovich, Vladimir; Mangala Prasad, Vidya; Nduati, Ruth; Sather, D Noah; Lee, Kelly K; Matsen Iv, Frederick A; Overbaugh, Julie.
Affiliation
  • Simonich CA; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
  • Doepker L; Medical Scientist Training Program, University of Washington School of Medicine, Seattle, WA, 98195, USA.
  • Ralph D; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
  • Williams JA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
  • Dhar A; Department of Medicinal Chemistry, University of Washington, Seattle, WA, 98195, USA.
  • Yaffe Z; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
  • Gentles L; Department of Statistics, University of Washington, Seattle, WA, 98195, USA.
  • Small CT; Medical Scientist Training Program, University of Washington School of Medicine, Seattle, WA, 98195, USA.
  • Oliver B; Department of Microbiology, University of Washington, Seattle, WA, 98195, USA.
  • Vigdorovich V; Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
  • Mangala Prasad V; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
  • Nduati R; Center for Infectious Disease Research, Seattle, WA, 98109, USA.
  • Sather DN; Center for Infectious Disease Research, Seattle, WA, 98109, USA.
  • Lee KK; Department of Medicinal Chemistry, University of Washington, Seattle, WA, 98195, USA.
  • Matsen Iv FA; Department of Pediatrics and Child Health, University of Nairobi, Nairobi, Kenya.
  • Overbaugh J; Center for Infectious Disease Research, Seattle, WA, 98109, USA.
Nat Commun ; 10(1): 2190, 2019 05 16.
Article in En | MEDLINE | ID: mdl-31097697
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Antibodies / HIV Infections / HIV-1 / Immunoglobulin kappa-Chains / Antibodies, Neutralizing Type of study: Prognostic_studies Limits: Humans / Infant Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Antibodies / HIV Infections / HIV-1 / Immunoglobulin kappa-Chains / Antibodies, Neutralizing Type of study: Prognostic_studies Limits: Humans / Infant Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Type: Article Affiliation country: United States