Effects of 1,8-cineole on neuropathic pain mediated by P2X2 receptor in the spinal cord dorsal horn.

Zheng, Xiao-Bo; Zhang, Ya-Ling; Li, Qing; Liu, Yi-Guo; Wang, Xiang-Dong; Yang, Bao-Lin; Zhu, Gao-Chun; Zhou, Cong-Fa; Gao, Yun; Liu, Zeng-Xu

Zheng, Xiao-Bo; Zhang, Ya-Ling; Li, Qing; Liu, Yi-Guo; Wang, Xiang-Dong; Yang, Bao-Lin; Zhu, Gao-Chun; Zhou, Cong-Fa; Gao, Yun; Liu, Zeng-Xu.

Affiliation

Zheng XB; Department of Anatomy, Medical School of Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China.
Zhang YL; Jiangxi Health Vocational College, Nanchang, 330052, Jiangxi, People's Republic of China.
Li Q; Department of Anatomy, Medical School of Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China.
Liu YG; Department of Anatomy, Medical School of Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China.
Wang XD; Grade 2018, Medical School of Tongji University, Shanghai, 310000, People's Republic of China.
Yang BL; Jiangxi Health Vocational College, Nanchang, 330052, Jiangxi, People's Republic of China.
Zhu GC; Department of Anatomy, Medical School of Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China.
Zhou CF; Department of Anatomy, Medical School of Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China.
Gao Y; Department of Anatomy, Medical School of Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China.
Liu ZX; Department of physiology, Basic Medical School, Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.

Sci Rep ; 9(1): 7909, 2019 05 27.

Article in En | MEDLINE | ID: mdl-31133659

Subject(s)

Eucalyptol/pharmacology; Neuralgia/drug therapy; Purinergic P2X Receptor Antagonists/pharmacology; Receptors, Purinergic P2X2/metabolism; Spinal Cord Compression/complications; Administration, Oral; Animals; Behavior Observation Techniques; Disease Models, Animal; Eucalyptol/therapeutic use; Female; Gene Expression Regulation/drug effects; Humans; Male; Neuralgia/diagnosis; Neuralgia/etiology; Neuralgia/pathology; Nociception/drug effects; Pain Measurement; Purinergic P2X Receptor Antagonists/therapeutic use; RNA, Messenger/metabolism; Rats; Receptors, Purinergic P2X2/genetics; Spinal Cord Compression/drug therapy; Spinal Cord Dorsal Horn/drug effects; Spinal Cord Dorsal Horn/injuries; Spinal Cord Dorsal Horn/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Cord Compression / Receptors, Purinergic P2X2 / Purinergic P2X Receptor Antagonists / Eucalyptol / Neuralgia Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Sci Rep Year: 2019 Type: Article

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