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PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein.
Thura, Min; Al-Aidaroos, Abdul Qader; Gupta, Abhishek; Chee, Cheng Ean; Lee, Soo Chin; Hui, Kam Man; Li, Jie; Guan, Yeoh Khay; Yong, Wei Peng; So, Jimmy; Chng, Wee Joo; Ng, Chin Hin; Zhou, Jianbiao; Wang, Ling Zhi; Yuen, John Shyi Peng; Ho, Henry Sun Sien; Yi, Sim Mei; Chiong, Edmund; Choo, Su Pin; Ngeow, Joanne; Ng, Matthew Chau Hsien; Chua, Clarinda; Yeo, Eugene Shen Ann; Tan, Iain Bee Huat; Sng, Joel Xuan En; Tan, Nicholas Yan Zhi; Thiery, Jean Paul; Goh, Boon Cher; Zeng, Qi.
Affiliation
  • Thura M; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.
  • Al-Aidaroos AQ; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.
  • Gupta A; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.
  • Chee CE; Department of Haematology-Oncology, National University Cancer Institute, Singapore (NCIS), Singapore, 119082, Singapore.
  • Lee SC; Department of Haematology-Oncology, National University Cancer Institute, Singapore (NCIS), Singapore, 119082, Singapore.
  • Hui KM; Division of Cellular and Molecular Research, National Cancer Centre Singapore, Singapore, 169610, Singapore.
  • Li J; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.
  • Guan YK; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119260, Singapore.
  • Yong WP; Department of Haematology-Oncology, National University Cancer Institute, Singapore (NCIS), Singapore, 119082, Singapore.
  • So J; Division of Surgical Oncology, National University Cancer Institute, Singapore (NCIS), Singapore, 119082, Singapore.
  • Chng WJ; Department of Haematology-Oncology, National University Cancer Institute, Singapore (NCIS), Singapore, 119082, Singapore.
  • Ng CH; Department of Haematology-Oncology, National University Cancer Institute, Singapore (NCIS), Singapore, 119082, Singapore.
  • Zhou J; Department of Haematology-Oncology, National University Cancer Institute, Singapore (NCIS), Singapore, 119082, Singapore.
  • Wang LZ; Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore.
  • Yuen JSP; Department of Urology, Singapore General Hospital, Singapore, 169608, Singapore.
  • Ho HSS; Department of Urology, Singapore General Hospital, Singapore, 169608, Singapore.
  • Yi SM; Department of Urology, Singapore General Hospital, Singapore, 169608, Singapore.
  • Chiong E; Division of Surgical Oncology, National University Cancer Institute, Singapore (NCIS), Singapore, 119082, Singapore.
  • Choo SP; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, 169610, Singapore.
  • Ngeow J; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.
  • Ng MCH; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, 169610, Singapore.
  • Chua C; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232, Singapore.
  • Yeo ESA; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, 169610, Singapore.
  • Tan IBH; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, 169610, Singapore.
  • Sng JXE; Department of Colorectal Surgery, Singapore General Hospital, Singapore, 169608, Singapore.
  • Tan NYZ; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, 169610, Singapore.
  • Thiery JP; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.
  • Goh BC; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.
  • Zeng Q; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.
Nat Commun ; 10(1): 2484, 2019 06 06.
Article in En | MEDLINE | ID: mdl-31171773
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Tyrosine Phosphatases / Carcinoma, Hepatocellular / Hepatocytes / Cytophagocytosis / Tumor Microenvironment / Antineoplastic Agents, Immunological / Liver Neoplasms / Antibody-Dependent Cell Cytotoxicity / Neoplasm Proteins Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Type: Article Affiliation country: Singapore
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Tyrosine Phosphatases / Carcinoma, Hepatocellular / Hepatocytes / Cytophagocytosis / Tumor Microenvironment / Antineoplastic Agents, Immunological / Liver Neoplasms / Antibody-Dependent Cell Cytotoxicity / Neoplasm Proteins Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Type: Article Affiliation country: Singapore