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2,4,5-Tris(alkoxyaryl)imidazoline derivatives as potent scaffold for novel p53-MDM2 interaction inhibitors: Design, synthesis, and biological evaluation.
Bazanov, Daniil R; Pervushin, Nikolay V; Savitskaya, Victoria Yu; Anikina, Lada V; Proskurnina, Marina V; Lozinskaya, Natalia A; Kopeina, Gelina S.
Affiliation
  • Bazanov DR; Department of Chemistry, M. V. Lomonosov Moscow State University, 1, Leninskie Gory, 119992 Moscow, Russian Federation.
  • Pervushin NV; Department of Medicine, M. V. Lomonosov Moscow State University, 1, Leninskie Gory, 119991 Moscow, Russian Federation.
  • Savitskaya VY; Department of Chemistry, M. V. Lomonosov Moscow State University, 1, Leninskie Gory, 119992 Moscow, Russian Federation.
  • Anikina LV; Institute of Physiologically Active Substances of RAS, 1, Northern Passage, 142432 Moscow Region, Russian Federation.
  • Proskurnina MV; Department of Chemistry, M. V. Lomonosov Moscow State University, 1, Leninskie Gory, 119992 Moscow, Russian Federation; Institute of Physiologically Active Substances of RAS, 1, Northern Passage, 142432 Moscow Region, Russian Federation.
  • Lozinskaya NA; Department of Chemistry, M. V. Lomonosov Moscow State University, 1, Leninskie Gory, 119992 Moscow, Russian Federation; Institute of Physiologically Active Substances of RAS, 1, Northern Passage, 142432 Moscow Region, Russian Federation. Electronic address: natalylozinskaya@mail.ru.
  • Kopeina GS; Department of Medicine, M. V. Lomonosov Moscow State University, 1, Leninskie Gory, 119991 Moscow, Russian Federation. Electronic address: lirroster@gmail.com.
Bioorg Med Chem Lett ; 29(16): 2364-2368, 2019 08 15.
Article in En | MEDLINE | ID: mdl-31196710
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / Tumor Suppressor Protein p53 / Imidazolines / Proto-Oncogene Proteins c-mdm2 / Small Molecule Libraries Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2019 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / Tumor Suppressor Protein p53 / Imidazolines / Proto-Oncogene Proteins c-mdm2 / Small Molecule Libraries Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2019 Type: Article