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Macropinocytosis in Cancer: A Complex Signaling Network.
Zhang, Yijuan; Commisso, Cosimo.
Affiliation
  • Zhang Y; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
  • Commisso C; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA. Electronic address: ccommisso@sbpdiscovery.org.
Trends Cancer ; 5(6): 332-334, 2019 06.
Article in En | MEDLINE | ID: mdl-31208695
ABSTRACT
Macropinocytosis is an important nutrient-scavenging pathway in numerous cancer types, including pancreatic, lung, prostate, and bladder. This Forum highlights recent work identifying the key regulators of macropinocytosis that support tumor cell fitness in different contexts, providing a unique framework for strategies to target macropinocytosis in the treatment of cancer.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pinocytosis / Signal Transduction / Neoplasms Limits: Animals / Humans Language: En Journal: Trends Cancer Year: 2019 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pinocytosis / Signal Transduction / Neoplasms Limits: Animals / Humans Language: En Journal: Trends Cancer Year: 2019 Type: Article Affiliation country: United States