Role of Nociceptor Toll-like Receptor 4 (TLR4) in Opioid-Induced Hyperalgesia and Hyperalgesic Priming.

Araldi, Dioneia; Bogen, Oliver; Green, Paul G; Levine, Jon D

Araldi, Dioneia; Bogen, Oliver; Green, Paul G; Levine, Jon D.

Affiliation

Araldi D; Department of Medicine.
Bogen O; Department of Oral and Maxillofacial Surgery.
Green PG; Division of Neuroscience, and.
Levine JD; Department of Medicine.

J Neurosci ; 39(33): 6414-6424, 2019 08 14.

Article in En | MEDLINE | ID: mdl-31209174

Subject(s)

Analgesics, Opioid/pharmacology; Hyperalgesia/metabolism; Morphine/pharmacology; Signal Transduction/drug effects; Toll-Like Receptor 4/metabolism; Animals; Hyperalgesia/chemically induced; Male; Neuronal Plasticity/drug effects; Rats; Rats, Sprague-Dawley

Key words

hyperalgesic priming; morphine; opioid-induced hyperalgesia (OIH); protein kinase epsilon (PKCÎµ); toll-like receptor 4 (TLR4)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Toll-Like Receptor 4 / Hyperalgesia / Analgesics, Opioid / Morphine Limits: Animals Language: En Journal: J Neurosci Year: 2019 Type: Article

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