Genetic basis of intracranial aneurysm formation and rupture: clinical implications in the postgenomic era.

Samuel, Nardin; Radovanovic, Ivan

Samuel, Nardin; Radovanovic, Ivan.

Affiliation

Samuel N; 1Division of Neurosurgery, Department of Surgery, University of Toronto; and.
Radovanovic I; 1Division of Neurosurgery, Department of Surgery, University of Toronto; and.

Neurosurg Focus ; 47(1): E10, 2019 07 01.

Article in En | MEDLINE | ID: mdl-31261114

Subject(s)

Aneurysm, Ruptured/genetics; Intracranial Aneurysm/genetics; Aneurysm, Ruptured/epidemiology; Disease Progression; Genetic Predisposition to Disease; Genomics; Humans; Intracranial Aneurysm/epidemiology; Risk Assessment; Subarachnoid Hemorrhage/epidemiology; Subarachnoid Hemorrhage/genetics

Key words

ADPKD = autosomal dominant polycystic kidney disease; DCI = delayed cerebral ischemia; EDS = Ehlers-Danlos syndrome; GWAS = genome-wide association studies; IAs = intracranial aneurysms; LDS = Loeys-Dietz syndrome; MMPs = matrix metalloproteases; NF1 = neurofibromatosis type 1; TSC = tuberous sclerosis complex; WES = whole-exome sequencing; aSAH = aneurysmal subarachnoid hemorrhage; eNOS = endothelial nitric oxide synthase; gene; genetic; intracranial aneurysm; polymorphism; risk

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Intracranial Aneurysm / Aneurysm, Ruptured Type of study: Etiology_studies / Prognostic_studies / Qualitative_research / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: Neurosurg Focus Journal subject: NEUROCIRURGIA Year: 2019 Type: Article

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