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Epigenetic silencing of TGFBI confers resistance to trastuzumab in human breast cancer.
Palomeras, Sònia; Diaz-Lagares, Ángel; Viñas, Gemma; Setien, Fernando; Ferreira, Humberto J; Oliveras, Glòria; Crujeiras, Ana B; Hernández, Alejandro; Lum, David H; Welm, Alana L; Esteller, Manel; Puig, Teresa.
Affiliation
  • Palomeras S; New Therapeutics Targets Lab (TargetsLab), Department of Medical Sciences, University of Girona, E-17071, Girona, Catalonia, Spain.
  • Diaz-Lagares Á; Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Hospitalet de Llobregat, Barcelona, Catalonia, Spain.
  • Viñas G; Cancer Epigenomics, Translational Medical Oncology (Oncomet), Health Research Institute of Santiago (IDIS), University Clinical Hospital of Santiago(CHUS/SERGAS), CIBERONC, Santiago de Compostela, Spain.
  • Setien F; New Therapeutics Targets Lab (TargetsLab), Department of Medical Sciences, University of Girona, E-17071, Girona, Catalonia, Spain.
  • Ferreira HJ; Medical Oncology Department, Catalan Institute of Oncology (ICO), Girona, Catalonia, Spain.
  • Oliveras G; Girona Biomedical Research Institute (IDIBGI), E-17071, Girona, Catalonia, Spain.
  • Crujeiras AB; Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Hospitalet de Llobregat, Barcelona, Catalonia, Spain.
  • Hernández A; Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Hospitalet de Llobregat, Barcelona, Catalonia, Spain.
  • Lum DH; New Therapeutics Targets Lab (TargetsLab), Department of Medical Sciences, University of Girona, E-17071, Girona, Catalonia, Spain.
  • Welm AL; Pathology Department, Dr. Josep Trueta Hospital and Catalan Institute of Health (ICS), E-17071, Girona, Catalonia, Spain.
  • Esteller M; Laboratory of Epigenomics in Endocrinology and Nutrition, Health Research Institute of Santiago (IDIS), University Clinical Hospital of Santiago (CHUS/SERGAS), Santiago de Compostela, Spain.
  • Puig T; CIBER Fisiopatologia de la Obesidad y Nutricion (CIBERobn), Santiago de Compostela, Spain.
Breast Cancer Res ; 21(1): 79, 2019 07 05.
Article in En | MEDLINE | ID: mdl-31277676
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Extracellular Matrix Proteins / Transforming Growth Factor beta / Drug Resistance, Neoplasm / Gene Silencing / Epigenesis, Genetic / Antineoplastic Agents Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Breast Cancer Res Journal subject: NEOPLASIAS Year: 2019 Type: Article Affiliation country: Spain
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Extracellular Matrix Proteins / Transforming Growth Factor beta / Drug Resistance, Neoplasm / Gene Silencing / Epigenesis, Genetic / Antineoplastic Agents Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Breast Cancer Res Journal subject: NEOPLASIAS Year: 2019 Type: Article Affiliation country: Spain