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Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model.
Rossaert, Elisabeth; Pollari, Eveliina; Jaspers, Tom; Van Helleputte, Lawrence; Jarpe, Matthew; Van Damme, Philip; De Bock, Katrien; Moisse, Matthieu; Van Den Bosch, Ludo.
Affiliation
  • Rossaert E; Department of Neurosciences, Experimental Neurology, and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Herestraat 49, 3000, Leuven, Belgium.
  • Pollari E; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Jaspers T; Department of Neurosciences, Experimental Neurology, and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Herestraat 49, 3000, Leuven, Belgium.
  • Van Helleputte L; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Jarpe M; Department of Neurosciences, Experimental Neurology, and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Herestraat 49, 3000, Leuven, Belgium.
  • Van Damme P; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • De Bock K; Department of Neurosciences, Experimental Neurology, and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Herestraat 49, 3000, Leuven, Belgium.
  • Moisse M; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Van Den Bosch L; Regenacy Pharmaceuticals Inc., Waltham, MA, USA.
Acta Neuropathol Commun ; 7(1): 107, 2019 07 05.
Article in En | MEDLINE | ID: mdl-31277703
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Histones / RNA-Binding Protein FUS / Disease Models, Animal / Metabolomics / Histone Deacetylase Inhibitors / Amyotrophic Lateral Sclerosis Type of study: Clinical_trials / Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Acta Neuropathol Commun Year: 2019 Type: Article Affiliation country: Belgium
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Histones / RNA-Binding Protein FUS / Disease Models, Animal / Metabolomics / Histone Deacetylase Inhibitors / Amyotrophic Lateral Sclerosis Type of study: Clinical_trials / Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Acta Neuropathol Commun Year: 2019 Type: Article Affiliation country: Belgium