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The Akt/mTOR cascade mediates high glucose-induced reductions in BDNF via DNMT1 in Schwann cells in diabetic peripheral neuropathy.
Zhang, Cui-Hong; Lv, Xin; Du, Wei; Cheng, Mei-Juan; Liu, Ya-Ping; Zhu, Lin; Hao, Jun.
Affiliation
  • Zhang CH; Department of Pathology, Hebei Medical University, Shijiazhuang, China; Department of Radiation Oncology, Bethune International Peace Hospital, Shijiazhuang, China.
  • Lv X; Department of Pathology, Hebei Medical University, Shijiazhuang, China.
  • Du W; Department of Pathology, Hebei Medical University, Shijiazhuang, China.
  • Cheng MJ; Department of Pathology, Hebei Medical University, Shijiazhuang, China.
  • Liu YP; Department of Pathology, Hebei Medical University, Shijiazhuang, China.
  • Zhu L; Department of Electromyogram, The Third Hospital of Hebei Medical University, Shijiazhuang, China. Electronic address: zhulin_930@163.com.
  • Hao J; Department of Pathology, Hebei Medical University, Shijiazhuang, China. Electronic address: haojun@hebmu.edu.cn.
Exp Cell Res ; 383(1): 111502, 2019 10 01.
Article in En | MEDLINE | ID: mdl-31323191
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schwann Cells / Gene Expression Regulation / Brain-Derived Neurotrophic Factor / Diabetic Neuropathies / Proto-Oncogene Proteins c-akt / TOR Serine-Threonine Kinases / Glucose Type of study: Etiology_studies Limits: Animals Language: En Journal: Exp Cell Res Year: 2019 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schwann Cells / Gene Expression Regulation / Brain-Derived Neurotrophic Factor / Diabetic Neuropathies / Proto-Oncogene Proteins c-akt / TOR Serine-Threonine Kinases / Glucose Type of study: Etiology_studies Limits: Animals Language: En Journal: Exp Cell Res Year: 2019 Type: Article Affiliation country: China