Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage.

Schiltz, Carl J; Lee, April; Partlow, Edward A; Hosford, Christopher J; Chappie, Joshua S

Schiltz, Carl J; Lee, April; Partlow, Edward A; Hosford, Christopher J; Chappie, Joshua S.

Affiliation

Schiltz CJ; Department of Molecular Medicine, Cornell University, Ithaca, NY 14853, USA.
Lee A; Department of Molecular Medicine, Cornell University, Ithaca, NY 14853, USA.
Partlow EA; Department of Molecular Medicine, Cornell University, Ithaca, NY 14853, USA.
Hosford CJ; Department of Molecular Medicine, Cornell University, Ithaca, NY 14853, USA.
Chappie JS; Department of Molecular Medicine, Cornell University, Ithaca, NY 14853, USA.

Nucleic Acids Res ; 47(17): 9448-9463, 2019 09 26.

Article in En | MEDLINE | ID: mdl-31400118

Subject(s)

Burkholderia pseudomallei/chemistry; Catalytic Domain/genetics; Deoxyribonucleases/ultrastructure; Protein Conformation; Xanthomonas/chemistry; Adenosine Triphosphatases/chemistry; Adenosine Triphosphatases/genetics; Amino Acid Sequence/genetics; Burkholderia pseudomallei/genetics; Catalysis; Deoxyribonucleases/chemistry; Deoxyribonucleases/genetics; Evolution, Molecular; Lysogeny/genetics; Metals/chemistry; Protein Domains/genetics; Sequence Alignment; Xanthomonas/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Conformation / Xanthomonas / Burkholderia pseudomallei / Catalytic Domain / Deoxyribonucleases Type of study: Prognostic_studies Language: En Journal: Nucleic Acids Res Year: 2019 Type: Article Affiliation country: United States

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