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A three-gene DNA methylation biomarker accurately classifies early stage prostate cancer.
Patel, Palak G; Wessel, Thomas; Kawashima, Atsunari; Okello, John B A; Jamaspishvili, Tamara; Guérard, Karl-Philippe; Lee, Laura; Lee, Anna Ying-Wah; How, Nathan E; Dion, Dan; Scarlata, Eleonora; Jackson, Chelsea L; Boursalie, Suzanne; Sack, Tanya; Dunn, Rachel; Moussa, Madeleine; Mackie/, Karen; Ellis, Audrey; Marra, Elizabeth; Chin, Joseph; Siddiqui, Khurram; Hetou, Khalil; Pickard, Lee-Anne; Arthur-Hayward, Vinolia; Bauman, Glenn; Chevalier, Simone; Brimo, Fadi; Boutros, Paul C; Lapointe PhD, Jacques; Bartlett, John M S; Gooding, Robert J; Berman, David M.
Affiliation
  • Patel PG; Department of Pathology & Molecular Medicine, Queen's University, Kingston, Ontario, Canada.
  • Wessel T; Division of Cancer Biology & Genetics, Queen's Cancer Research Institute, Queen's University, Kingston, Ontario, Canada.
  • Kawashima A; Life Sciences Group, Thermo Fisher Scientific, Waltham, Massachusetts.
  • Okello JBA; Department of Pathology & Molecular Medicine, Queen's University, Kingston, Ontario, Canada.
  • Jamaspishvili T; Division of Cancer Biology & Genetics, Queen's Cancer Research Institute, Queen's University, Kingston, Ontario, Canada.
  • Guérard KP; Department of Urology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.
  • Lee L; Department of Pathology & Molecular Medicine, Queen's University, Kingston, Ontario, Canada.
  • Lee AY; Division of Cancer Biology & Genetics, Queen's Cancer Research Institute, Queen's University, Kingston, Ontario, Canada.
  • How NE; Cardiac Genome Clinic, Ted Rogers Centre for Heart Research, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Dion D; Department of Pathology & Molecular Medicine, Queen's University, Kingston, Ontario, Canada.
  • Scarlata E; Division of Cancer Biology & Genetics, Queen's Cancer Research Institute, Queen's University, Kingston, Ontario, Canada.
  • Jackson CL; Division of Urology, Department of Surgery, McGill University and the Research Institute of the McGill University Health Centre, Montreal, Québec, Canada.
  • Boursalie S; Ontario Institute for Cancer Research (OICR), Toronto, Ontario, Canada.
  • Sack T; Ontario Institute for Cancer Research (OICR), Toronto, Ontario, Canada.
  • Dunn R; Department of Pathology & Molecular Medicine, Queen's University, Kingston, Ontario, Canada.
  • Moussa M; Division of Cancer Biology & Genetics, Queen's Cancer Research Institute, Queen's University, Kingston, Ontario, Canada.
  • Mackie/ K; Ontario Institute for Cancer Research (OICR), Toronto, Ontario, Canada.
  • Ellis A; Division of Urology, Department of Surgery, McGill University and the Research Institute of the McGill University Health Centre, Montreal, Québec, Canada.
  • Marra E; Department of Pathology & Molecular Medicine, Queen's University, Kingston, Ontario, Canada.
  • Chin J; Division of Cancer Biology & Genetics, Queen's Cancer Research Institute, Queen's University, Kingston, Ontario, Canada.
  • Siddiqui K; Department of Pathology & Molecular Medicine, Queen's University, Kingston, Ontario, Canada.
  • Hetou K; Division of Cancer Biology & Genetics, Queen's Cancer Research Institute, Queen's University, Kingston, Ontario, Canada.
  • Pickard LA; Department of Pathology & Molecular Medicine, Queen's University, Kingston, Ontario, Canada.
  • Arthur-Hayward V; Division of Cancer Biology & Genetics, Queen's Cancer Research Institute, Queen's University, Kingston, Ontario, Canada.
  • Bauman G; Department of Pathology & Molecular Medicine, Queen's University, Kingston, Ontario, Canada.
  • Chevalier S; Division of Cancer Biology & Genetics, Queen's Cancer Research Institute, Queen's University, Kingston, Ontario, Canada.
  • Brimo F; Division of Surgical Pathology, Departmant of Pathology and Laboratory Medicine, London Health Sciences Centre, London, Ontario, Canada.
  • Boutros PC; Division of Surgical Pathology, Departmant of Pathology and Laboratory Medicine, London Health Sciences Centre, London, Ontario, Canada.
  • Lapointe PhD J; Division of Surgical Pathology, Departmant of Pathology and Laboratory Medicine, London Health Sciences Centre, London, Ontario, Canada.
  • Bartlett JMS; Division of Surgical Pathology, Departmant of Pathology and Laboratory Medicine, London Health Sciences Centre, London, Ontario, Canada.
  • Gooding RJ; Department of Surgery (Urology), London Health Sciences Centre, London, ON, Canada.
  • Berman DM; Department of Surgery (Urology), London Health Sciences Centre, London, ON, Canada.
Prostate ; 79(14): 1705-1714, 2019 10.
Article in En | MEDLINE | ID: mdl-31433512
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Biomarkers, Tumor / DNA Methylation Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans / Male Language: En Journal: Prostate Year: 2019 Type: Article Affiliation country: Canada
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Biomarkers, Tumor / DNA Methylation Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans / Male Language: En Journal: Prostate Year: 2019 Type: Article Affiliation country: Canada