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Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity.
Solis, Angel G; Bielecki, Piotr; Steach, Holly R; Sharma, Lokesh; Harman, Christian C D; Yun, Sanguk; de Zoete, Marcel R; Warnock, James N; To, S D Filip; York, Autumn G; Mack, Matthias; Schwartz, Martin A; Dela Cruz, Charles S; Palm, Noah W; Jackson, Ruaidhrí; Flavell, Richard A.
Affiliation
  • Solis AG; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Bielecki P; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Steach HR; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Sharma L; Department of Internal Medicine, Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Harman CCD; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
  • Yun S; Department of Internal Medicine (Cardiology), Yale Cardiovascular Research Center, Yale University, New Haven, CT, USA.
  • de Zoete MR; Department of Cell Biology, Yale Cardiovascular Research Center, Yale University, New Haven, CT, USA.
  • Warnock JN; Department of Biomedical Engineering, Yale Cardiovascular Research Center, Yale University, Yale University, New Haven, CT, USA.
  • To SDF; Department of Infectious Diseases and Immunology, Utrecht University, Utrecht, The Netherlands.
  • York AG; School of Chemical, Materials and Biomedical Engineering, University of Georgia, Athens, GA, USA.
  • Mack M; Department of Agricultural and Biological Engineering, Mississippi State University, Mississippi State, MS, USA.
  • Schwartz MA; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Dela Cruz CS; Department of Internal Medicine II-Nephrology, University Hospital Regensburg, Regensburg, Germany.
  • Palm NW; Department of Internal Medicine (Cardiology), Yale Cardiovascular Research Center, Yale University, New Haven, CT, USA.
  • Jackson R; Department of Cell Biology, Yale Cardiovascular Research Center, Yale University, New Haven, CT, USA.
  • Flavell RA; Department of Biomedical Engineering, Yale Cardiovascular Research Center, Yale University, Yale University, New Haven, CT, USA.
Nature ; 573(7772): 69-74, 2019 09.
Article in En | MEDLINE | ID: mdl-31435009
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mechanotransduction, Cellular / Hydrostatic Pressure / Immunity, Innate / Ion Channels Limits: Animals Language: En Journal: Nature Year: 2019 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mechanotransduction, Cellular / Hydrostatic Pressure / Immunity, Innate / Ion Channels Limits: Animals Language: En Journal: Nature Year: 2019 Type: Article Affiliation country: United States