Your browser doesn't support javascript.
loading
Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism.
Zhong, Wenhe; Pasunooti, Kalyan Kumar; Balamkundu, Seetharamsing; Wong, Yee Hwa; Nah, Qianhui; Gadi, Vinod; Gnanakalai, Shanmugavel; Chionh, Yok Hian; McBee, Megan E; Gopal, Pooja; Lim, Siau Hoi; Olivier, Nelson; Buurman, Ed T; Dick, Thomas; Liu, Chuan Fa; Lescar, Julien; Dedon, Peter C.
Affiliation
  • Zhong W; Infectious Disease and Antimicrobial Resistance Interdisciplinary Research Groups , Singapore-MIT Alliance for Research and Technology , 1 CREATE Way , 138602 Singapore.
  • Pasunooti KK; NTU Institute of Structural Biology , Nanyang Technological University , 636921 Singapore.
  • Balamkundu S; Infectious Disease and Antimicrobial Resistance Interdisciplinary Research Groups , Singapore-MIT Alliance for Research and Technology , 1 CREATE Way , 138602 Singapore.
  • Wong YH; Infectious Disease and Antimicrobial Resistance Interdisciplinary Research Groups , Singapore-MIT Alliance for Research and Technology , 1 CREATE Way , 138602 Singapore.
  • Nah Q; School of Biological Sciences , Nanyang Technological University , 60 Nanyang Drive , 637551 Singapore.
  • Gadi V; NTU Institute of Structural Biology , Nanyang Technological University , 636921 Singapore.
  • Gnanakalai S; Infectious Disease and Antimicrobial Resistance Interdisciplinary Research Groups , Singapore-MIT Alliance for Research and Technology , 1 CREATE Way , 138602 Singapore.
  • Chionh YH; Infectious Disease and Antimicrobial Resistance Interdisciplinary Research Groups , Singapore-MIT Alliance for Research and Technology , 1 CREATE Way , 138602 Singapore.
  • McBee ME; Infectious Disease and Antimicrobial Resistance Interdisciplinary Research Groups , Singapore-MIT Alliance for Research and Technology , 1 CREATE Way , 138602 Singapore.
  • Gopal P; Infectious Disease and Antimicrobial Resistance Interdisciplinary Research Groups , Singapore-MIT Alliance for Research and Technology , 1 CREATE Way , 138602 Singapore.
  • Lim SH; Infectious Disease and Antimicrobial Resistance Interdisciplinary Research Groups , Singapore-MIT Alliance for Research and Technology , 1 CREATE Way , 138602 Singapore.
  • Olivier N; Yong Loo Lin School of Medicine , National University of Singapore , 117597 Singapore.
  • Buurman ET; School of Biological Sciences , Nanyang Technological University , 60 Nanyang Drive , 637551 Singapore.
  • Lescar J; Yong Loo Lin School of Medicine , National University of Singapore , 117597 Singapore.
  • Dedon PC; School of Biological Sciences , Nanyang Technological University , 60 Nanyang Drive , 637551 Singapore.
J Med Chem ; 62(17): 7788-7805, 2019 09 12.
Article in En | MEDLINE | ID: mdl-31442049
Subject(s)
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / TRNA Methyltransferases / Tyrosine / Enzyme Inhibitors Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2019 Type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / TRNA Methyltransferases / Tyrosine / Enzyme Inhibitors Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2019 Type: Article