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Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1.
Jung, Su Myung; Hung, Chien-Min; Hildebrand, Samuel R; Sanchez-Gurmaches, Joan; Martinez-Pastor, Barbara; Gengatharan, Jivani M; Wallace, Martina; Mukhopadhyay, Dimpi; Martinez Calejman, Camila; Luciano, Amelia K; Hsiao, Wen-Yu; Tang, Yuefeng; Li, Huawei; Daniels, Danette L; Mostoslavsky, Raul; Metallo, Christian M; Guertin, David A.
Affiliation
  • Jung SM; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Hung CM; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Hildebrand SR; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Sanchez-Gurmaches J; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA; Division of Endocrinology, Developmental Biology, Cincinnati Children's Hospital Research Foundation, University of Cincinnati College of Medicine, Cincinnati, OH 45209, USA; Department of Pediatrics
  • Martinez-Pastor B; The Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA.
  • Gengatharan JM; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA.
  • Wallace M; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA.
  • Mukhopadhyay D; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Martinez Calejman C; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Luciano AK; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Hsiao WY; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Tang Y; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Li H; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Daniels DL; Promega Corporation, 2800 Woods Hollow Road, Madison, WI 53711, USA.
  • Mostoslavsky R; The Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA.
  • Metallo CM; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA.
  • Guertin DA; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address: david.guertin@umassmed.edu.
Mol Cell ; 75(4): 807-822.e8, 2019 08 22.
Article in En | MEDLINE | ID: mdl-31442424
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sirtuins / Adipocytes, Brown / Forkhead Box Protein O1 / Mechanistic Target of Rapamycin Complex 2 / Lipolysis Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2019 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sirtuins / Adipocytes, Brown / Forkhead Box Protein O1 / Mechanistic Target of Rapamycin Complex 2 / Lipolysis Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2019 Type: Article Affiliation country: United States