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Cyclophosphamide Enhances Cancer Antibody Immunotherapy in the Resistant Bone Marrow Niche by Modulating Macrophage FcγR Expression.
Roghanian, Ali; Hu, Guangan; Fraser, Christopher; Singh, Maneesh; Foxall, Russell B; Meyer, Matthew J; Lees, Emma; Huet, Heather; Glennie, Martin J; Beers, Stephen A; Lim, Sean H; Ashton-Key, Margaret; Thirdborough, Stephen M; Cragg, Mark S; Chen, Jianzhu.
Affiliation
  • Roghanian A; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts. a.roghanian@soton.ac.uk aroghani@mit.edu jchen@mit.edu.
  • Hu G; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Fraser C; Cancer Research UK Centre, University of Southampton, Southampton, United Kindgom.
  • Singh M; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • Foxall RB; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • Meyer MJ; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • Lees E; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Huet H; Cancer Research UK Centre, University of Southampton, Southampton, United Kindgom.
  • Glennie MJ; Novartis Institute for Biomedical Research, Inc., Cambridge, Massachusetts.
  • Beers SA; Novartis Institute for Biomedical Research, Inc., Cambridge, Massachusetts.
  • Lim SH; Novartis Institute for Biomedical Research, Inc., Cambridge, Massachusetts.
  • Ashton-Key M; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Thirdborough SM; Cancer Research UK Centre, University of Southampton, Southampton, United Kindgom.
  • Cragg MS; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Chen J; Cancer Research UK Centre, University of Southampton, Southampton, United Kindgom.
Cancer Immunol Res ; 7(11): 1876-1890, 2019 11.
Article in En | MEDLINE | ID: mdl-31451483
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow / Receptors, IgG / Drug Resistance, Neoplasm / Cyclophosphamide / Antineoplastic Agents, Immunological / Macrophages Limits: Animals / Humans Language: En Journal: Cancer Immunol Res Year: 2019 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow / Receptors, IgG / Drug Resistance, Neoplasm / Cyclophosphamide / Antineoplastic Agents, Immunological / Macrophages Limits: Animals / Humans Language: En Journal: Cancer Immunol Res Year: 2019 Type: Article