Cytolinker Gas2L1 regulates axon morphology through microtubule-modulated actin stabilization.

van de Willige, Dieudonnée; Hummel, Jessica Ja; Alkemade, Celine; Kahn, Olga I; Au, Franco Kc; Qi, Robert Z; Dogterom, Marileen; Koenderink, Gijsje H; Hoogenraad, Casper C; Akhmanova, Anna

van de Willige, Dieudonnée; Hummel, Jessica Ja; Alkemade, Celine; Kahn, Olga I; Au, Franco Kc; Qi, Robert Z; Dogterom, Marileen; Koenderink, Gijsje H; Hoogenraad, Casper C; Akhmanova, Anna.

Affiliation

van de Willige D; Department of Biology, Cell Biology, Faculty of Science, Utrecht University, Utrecht, The Netherlands.
Hummel JJ; Department of Biology, Cell Biology, Faculty of Science, Utrecht University, Utrecht, The Netherlands.
Alkemade C; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, The Netherlands.
Kahn OI; Living Matter Department, AMOLF, Amsterdam, The Netherlands.
Au FK; Department of Biology, Cell Biology, Faculty of Science, Utrecht University, Utrecht, The Netherlands.
Qi RZ; Division of Life Science and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Hong Kong, China.
Dogterom M; Division of Life Science and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Hong Kong, China.
Koenderink GH; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, The Netherlands.
Hoogenraad CC; Living Matter Department, AMOLF, Amsterdam, The Netherlands.
Akhmanova A; Department of Biology, Cell Biology, Faculty of Science, Utrecht University, Utrecht, The Netherlands.

EMBO Rep ; 20(11): e47732, 2019 11 05.

Article in En | MEDLINE | ID: mdl-31486213

Subject(s)

Actins/metabolism; Axons/metabolism; Microfilament Proteins/metabolism; Microtubules/metabolism; Neurons/cytology; Neurons/metabolism; Animals; Biomarkers; COS Cells; Chlorocebus aethiops; Female; HEK293 Cells; Hippocampus/metabolism; Humans; Male; Molecular Imaging; Neurites/metabolism; Protein Binding; Protein Stability; Protein Transport; Pyramidal Cells/cytology; Pyramidal Cells/metabolism; Rats

Key words

axon; cytolinker; cytoskeleton; in vitro reconstitution; neuronal development

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Axons / Actins / Microfilament Proteins / Microtubules / Neurons Limits: Animals / Female / Humans / Male Language: En Journal: EMBO Rep Journal subject: BIOLOGIA MOLECULAR Year: 2019 Type: Article Affiliation country: Netherlands

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