Penicillin allergy skin testing as an antibiotic stewardship intervention reduces alternative antibiotic exposures in hematopoietic stem cell transplant recipients.

Modi, Anita R; Majhail, Navneet S; Rybicki, Lisa; Athans, Vasilios; Carlstrom, Kelley; Srinivas, Pavithra; Lang, David M; Sobecks, Ronald; Kovacs, Christopher S

Modi, Anita R; Majhail, Navneet S; Rybicki, Lisa; Athans, Vasilios; Carlstrom, Kelley; Srinivas, Pavithra; Lang, David M; Sobecks, Ronald; Kovacs, Christopher S.

Affiliation

Modi AR; Department of Infectious Diseases, Respiratory Institute, Cleveland Clinic, Cleveland, OH, USA.
Majhail NS; Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
Rybicki L; Transplantation Center, Cleveland Clinic, Cleveland, OH, USA.
Athans V; Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA.
Carlstrom K; Department of Pharmacy, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Srinivas P; Department of Pharmacy Services, Cleveland Clinic, Cleveland, OH, USA.
Lang DM; Department of Pharmacy Services, Cleveland Clinic, Cleveland, OH, USA.
Sobecks R; Department of Allergy and Clinical Immunology, Respiratory Institute, Cleveland Clinic, Cleveland, OH, USA.
Kovacs CS; Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.

Transpl Infect Dis ; 21(6): e13175, 2019 Dec.

Article in En | MEDLINE | ID: mdl-31539459

Subject(s)

Anti-Bacterial Agents/adverse effects; Antimicrobial Stewardship/methods; Clostridium Infections/prevention & control; Drug Hypersensitivity/diagnosis; Hematopoietic Stem Cell Transplantation/adverse effects; Penicillins/adverse effects; Adolescent; Adult; Aged; Anti-Bacterial Agents/administration & dosage; Anti-Bacterial Agents/economics; Antimicrobial Stewardship/economics; Antimicrobial Stewardship/standards; Clostridioides difficile/immunology; Clostridium Infections/epidemiology; Clostridium Infections/immunology; Drug Costs; Drug Hypersensitivity/etiology; Female; Graft Rejection/immunology; Graft Rejection/prevention & control; Health Plan Implementation/economics; Humans; Immunocompromised Host; Immunosuppressive Agents/adverse effects; Incidence; Male; Middle Aged; Penicillins/administration & dosage; Penicillins/economics; Practice Guidelines as Topic; Program Evaluation; Retrospective Studies; Skin Tests/economics; Young Adult

Key words

allergy; antibiotic; beta-lactam; de-labeling; penicillin; stem cell transplant; stewardship

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Penicillins / Clostridium Infections / Hematopoietic Stem Cell Transplantation / Drug Hypersensitivity / Antimicrobial Stewardship / Anti-Bacterial Agents Type of study: Etiology_studies / Evaluation_studies / Guideline / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Sysrev_observational_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Transpl Infect Dis Journal subject: TRANSPLANTE Year: 2019 Type: Article Affiliation country: United States

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