Strategy to minimize radiation burden in infants and high-risk medulloblastoma using intrathecal methotrexate and high-dose chemotherapy: A prospective registry study in Japan.

Yamasaki, Kai; Okada, Keiko; Soejima, Toshinori; Sakamoto, Hiroaki; Hara, Junichi

Yamasaki, Kai; Okada, Keiko; Soejima, Toshinori; Sakamoto, Hiroaki; Hara, Junichi.

Affiliation

Yamasaki K; Department of Pediatric Hematology and Oncology, Osaka City General Hospital, Osaka, Japan.
Okada K; Department of Pediatric Hematology and Oncology, Osaka City General Hospital, Osaka, Japan.
Soejima T; Department of Radiation Oncology, Kobe Proton Center, Kobe, Japan.
Sakamoto H; Department of Pediatric Neurosurgery, Osaka City General Hospital, Osaka, Japan.
Hara J; Department of Pediatric Hematology and Oncology, Osaka City General Hospital, Osaka, Japan.

Pediatr Blood Cancer ; 67(1): e28012, 2020 01.

Article in En | MEDLINE | ID: mdl-31544362

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Cerebellar Neoplasms/drug therapy; Medulloblastoma/drug therapy; Registries/statistics & numerical data; Adolescent; Cerebellar Neoplasms/pathology; Cerebellar Neoplasms/radiotherapy; Child; Child, Preschool; Cisplatin/administration & dosage; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide/administration & dosage; Etoposide/administration & dosage; Female; Follow-Up Studies; Humans; Injections, Spinal; Male; Medulloblastoma/pathology; Medulloblastoma/radiotherapy; Melphalan/administration & dosage; Methotrexate/administration & dosage; Prognosis; Prospective Studies; Survival Rate

Key words

chemotherapy; craniospinal irradiation; intrathecal methotrexate; medulloblastoma; radiotherapy; thiotepa

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Cerebellar Neoplasms / Registries / Medulloblastoma Type of study: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Male Language: En Journal: Pediatr Blood Cancer Journal subject: HEMATOLOGIA / NEOPLASIAS / PEDIATRIA Year: 2020 Type: Article Affiliation country: Japan

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