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Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer.
Mameishvili, Ekaterina; Serafimidis, Ioannis; Iwaszkiewicz, Sara; Lesche, Mathias; Reinhardt, Susanne; Bölicke, Nora; Büttner, Maren; Stellas, Dimitris; Papadimitropoulou, Adriana; Szabolcs, Matthias; Anastassiadis, Konstantinos; Dahl, Andreas; Theis, Fabian; Efstratiadis, Argiris; Gavalas, Anthony.
Affiliation
  • Mameishvili E; Paul Langerhans Institute Dresden, Helmholtz Center Munich at the University Clinic Carl Gustav Carus of Technische Universität Dresden, German Research Center for Environmental Health, Helmholtz Zentrum München, D-85764 Neuherberg, Germany.
  • Serafimidis I; German Centre for Diabetes Research (DZD e.V.), D-85764 Neuherberg, Germany.
  • Iwaszkiewicz S; Biomedical Research Foundation of the Academy of Athens, 115 27 Athens, Greece.
  • Lesche M; Paul Langerhans Institute Dresden, Helmholtz Center Munich at the University Clinic Carl Gustav Carus of Technische Universität Dresden, German Research Center for Environmental Health, Helmholtz Zentrum München, D-85764 Neuherberg, Germany.
  • Reinhardt S; German Centre for Diabetes Research (DZD e.V.), D-85764 Neuherberg, Germany.
  • Bölicke N; Paul Langerhans Institute Dresden, Helmholtz Center Munich at the University Clinic Carl Gustav Carus of Technische Universität Dresden, German Research Center for Environmental Health, Helmholtz Zentrum München, D-85764 Neuherberg, Germany.
  • Büttner M; German Centre for Diabetes Research (DZD e.V.), D-85764 Neuherberg, Germany.
  • Stellas D; Biotechnology Center, Technische Universität Dresden, 01307 Dresden, Germany.
  • Papadimitropoulou A; Biotechnology Center, Technische Universität Dresden, 01307 Dresden, Germany.
  • Szabolcs M; Paul Langerhans Institute Dresden, Helmholtz Center Munich at the University Clinic Carl Gustav Carus of Technische Universität Dresden, German Research Center for Environmental Health, Helmholtz Zentrum München, D-85764 Neuherberg, Germany.
  • Anastassiadis K; Center for Regenerative Therapies Dresden, Faculty of Medicine, Technische Universität Dresden, 01307 Dresden, Germany.
  • Dahl A; Institute of Computational Biology, German Research Center for Environmental Health, Helmholtz Zentrum München, D-85764 Neuherberg, Germany.
  • Theis F; Biomedical Research Foundation of the Academy of Athens, 115 27 Athens, Greece.
  • Efstratiadis A; Biomedical Research Foundation of the Academy of Athens, 115 27 Athens, Greece.
  • Gavalas A; Department of Pathology and Cell Biology, Columbia University Medical Center, NY 10032.
Proc Natl Acad Sci U S A ; 116(41): 20679-20688, 2019 10 08.
Article in En | MEDLINE | ID: mdl-31548432
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Stem Cells / Cell Transformation, Neoplastic / Proto-Oncogene Proteins p21(ras) / Carcinoma, Pancreatic Ductal / Aldehyde Dehydrogenase, Mitochondrial / Aldehyde Dehydrogenase 1 Family / Mutation Type of study: Prognostic_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2019 Type: Article Affiliation country: Germany
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Stem Cells / Cell Transformation, Neoplastic / Proto-Oncogene Proteins p21(ras) / Carcinoma, Pancreatic Ductal / Aldehyde Dehydrogenase, Mitochondrial / Aldehyde Dehydrogenase 1 Family / Mutation Type of study: Prognostic_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2019 Type: Article Affiliation country: Germany