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High levels of Notch intracellular cleaved domain are associated with stemness and reduced bevacizumab efficacy in patients with advanced colon cancer.
Negri, Francesca; Bozzetti, Cecilia; Pedrazzi, Giuseppe; Azzoni, Cinzia; Bottarelli, Lorena; Squadrilli, Anna; Lagrasta, Costanza; Tamagnini, Ione; Bisagni, Alessandra; Ragazzi, Moira; Porzio, Rosa; Tomasello, Gianluca; Mori, Daniele; Leonardi, Francesco; Gnetti, Letizia; Crafa, Pellegrino; Sala, Roberto; Cascinu, Stefano.
Affiliation
  • Negri F; Medical Oncology Unit, University Hospital of Parma, I­43126 Parma, Italy.
  • Bozzetti C; Medical Oncology Unit, University Hospital of Parma, I­43126 Parma, Italy.
  • Pedrazzi G; Department of Medicine and Surgery, Unit of Neuroscience and Robust Statistics Academy (Ro.S.A.), University of Parma, I­43126 Parma, Italy.
  • Azzoni C; Department of Medicine and Surgery, Unit of Pathological Anatomy, University Hospital of Parma, I­43126 Parma, Italy.
  • Bottarelli L; Department of Medicine and Surgery, Unit of Pathological Anatomy, University Hospital of Parma, I­43126 Parma, Italy.
  • Squadrilli A; Medical Oncology Unit, University Hospital of Parma, I­43126 Parma, Italy.
  • Lagrasta C; Department of Medicine and Surgery, Unit of Pathological Anatomy, University Hospital of Parma, I­43126 Parma, Italy.
  • Tamagnini I; Pathology Unit, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS), Santa Maria Nuova Hospital, I­42123 Reggio Emilia, Italy.
  • Bisagni A; Pathology Unit, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS), Santa Maria Nuova Hospital, I­42123 Reggio Emilia, Italy.
  • Ragazzi M; Pathology Unit, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS), Santa Maria Nuova Hospital, I­42123 Reggio Emilia, Italy.
  • Porzio R; Department of Oncology­Haematology, G. da Saliceto Hospital, I­29121 Piacenza, Italy.
  • Tomasello G; Medical Oncology Unit, ASST Ospedale di Cremona, I­26100 Cremona, Italy.
  • Mori D; Department of Medicine and Surgery, General Pathology, University of Parma, I­43126 Parma, Italy.
  • Leonardi F; Medical Oncology Unit, University Hospital of Parma, I­43126 Parma, Italy.
  • Gnetti L; Department of Medicine and Surgery, Unit of Pathological Anatomy, University Hospital of Parma, I­43126 Parma, Italy.
  • Crafa P; Department of Medicine and Surgery, Unit of Pathological Anatomy, University Hospital of Parma, I­43126 Parma, Italy.
  • Sala R; Department of Medicine and Surgery, General Pathology, University of Parma, I­43126 Parma, Italy.
  • Cascinu S; Division of Medical Oncology, University Hospital of Modena and Reggio Emilia, I­41124 Modena, Italy.
Oncol Rep ; 42(6): 2750-2758, 2019 Dec.
Article in En | MEDLINE | ID: mdl-31578584
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Calcium-Binding Proteins / Colonic Neoplasms / Hyaluronan Receptors / Adaptor Proteins, Signal Transducing / Bevacizumab / Neovascularization, Pathologic Type of study: Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Oncol Rep Journal subject: NEOPLASIAS Year: 2019 Type: Article Affiliation country: Italy
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Calcium-Binding Proteins / Colonic Neoplasms / Hyaluronan Receptors / Adaptor Proteins, Signal Transducing / Bevacizumab / Neovascularization, Pathologic Type of study: Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Oncol Rep Journal subject: NEOPLASIAS Year: 2019 Type: Article Affiliation country: Italy