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What Makes Polysorbate Functional? Impact of Polysorbate 80 Grade and Quality on IgG Stability During Mechanical Stress.
Grabarek, Adam Dariusz; Bozic, Ula; Rousel, Jannik; Menzen, Tim; Kranz, Wendelin; Wuchner, Klaus; Jiskoot, Wim; Hawe, Andrea.
Affiliation
  • Grabarek AD; Coriolis Pharma Research, Fraunhoferstr. 18b, 82152 Martinsried, Germany; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, PO Box 9502, 2300 RA Leiden, The Netherlands.
  • Bozic U; Coriolis Pharma Research, Fraunhoferstr. 18b, 82152 Martinsried, Germany.
  • Rousel J; Coriolis Pharma Research, Fraunhoferstr. 18b, 82152 Martinsried, Germany; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, PO Box 9502, 2300 RA Leiden, The Netherlands.
  • Menzen T; Coriolis Pharma Research, Fraunhoferstr. 18b, 82152 Martinsried, Germany.
  • Kranz W; Coriolis Pharma Research, Fraunhoferstr. 18b, 82152 Martinsried, Germany.
  • Wuchner K; Janssen Research & Development, Pharmaceutical Development & Manufacturing Sciences, Large Molecule Analytical Development, Schaffhausen, Switzerland.
  • Jiskoot W; Coriolis Pharma Research, Fraunhoferstr. 18b, 82152 Martinsried, Germany; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, PO Box 9502, 2300 RA Leiden, The Netherlands.
  • Hawe A; Coriolis Pharma Research, Fraunhoferstr. 18b, 82152 Martinsried, Germany. Electronic address: andrea.hawe@coriolis-pharma.com.
J Pharm Sci ; 109(1): 871-880, 2020 01.
Article in En | MEDLINE | ID: mdl-31614127
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysorbates / Surface-Active Agents / Immunoglobulin G / Antibodies, Monoclonal Language: En Journal: J Pharm Sci Year: 2020 Type: Article Affiliation country: Netherlands
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysorbates / Surface-Active Agents / Immunoglobulin G / Antibodies, Monoclonal Language: En Journal: J Pharm Sci Year: 2020 Type: Article Affiliation country: Netherlands