Mechanisms of ischaemic neural progenitor proliferation: a regulatory role of the HIF-1&#945;-CBX7 pathway.

Chiu, H-Y; Lee, H-T; Lee, K-H; Zhao, Y; Hsu, C Y; Shyu, W C

Mechanisms of ischaemic neural progenitor proliferation: a regulatory role of the HIF-1α-CBX7 pathway.

Chiu, H-Y; Lee, H-T; Lee, K-H; Zhao, Y; Hsu, C Y; Shyu, W C.

Affiliation

Chiu HY; Children's Hospital, China Medical University and Hospital, Taichung, Taiwan.
Lee HT; Department of Neurosurgery, Taichung Veterans General Hospital, Taichung, Taiwan.
Lee KH; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan.
Zhao Y; Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA.
Hsu CY; Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA.
Shyu WC; Graduate Institute of Biomedical Science and Drug Development Center, China Medical University, Taichung, Taiwan.

Neuropathol Appl Neurobiol ; 46(4): 391-405, 2020 06.

Article in En | MEDLINE | ID: mdl-31630421

Subject(s)

Gene Expression Regulation/physiology; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism; Hypoxia-Ischemia, Brain/metabolism; Neural Stem Cells/metabolism; Polycomb Repressive Complex 1/metabolism; Animals; Cell Hypoxia/physiology; Cell Proliferation/physiology; Mice; Mice, Inbred C57BL; Mice, Knockout; Rats

Key words

cell trafficking; cerebral ischaemia; hypoxia; hypoxia-inducible factor 1α (HIF-1α); neural progenitor cells (NPCs); polycomb repressor complex 1-chromobox7 (CBX7)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Hypoxia-Ischemia, Brain / Hypoxia-Inducible Factor 1, alpha Subunit / Neural Stem Cells / Polycomb Repressive Complex 1 Limits: Animals Language: En Journal: Neuropathol Appl Neurobiol Year: 2020 Type: Article Affiliation country: Taiwan

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