A biochemometrics strategy for tracing diuretic components of crude and processed Alisma orientale based on quantitative determination and pharmacological evaluation.

Tao, Yi; Jiang, Enci; Yan, Jizhong; Cai, Baochang

Tao, Yi; Jiang, Enci; Yan, Jizhong; Cai, Baochang.

Affiliation

Tao Y; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
Jiang E; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
Yan J; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
Cai B; Jiangsu Key Laboratory of Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing, China.

Biomed Chromatogr ; 34(2): e4744, 2020 Feb.

Article in En | MEDLINE | ID: mdl-31725908

Subject(s)

Alisma/chemistry; Diuretics; Plant Extracts/chemistry; Animals; Chromatography, Liquid; Diuretics/chemistry; Diuretics/pharmacology; Diuretics/urine; Limit of Detection; Linear Models; Male; Mice; Reproducibility of Results; Tandem Mass Spectrometry; Triterpenes/chemistry; Triterpenes/pharmacology; Triterpenes/urine; Urination/drug effects

Key words

UHPLC-MS/MS; biochemometrics; canonical correlation analysis; diuretic effect; salt processed

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plant Extracts / Alisma / Diuretics Type of study: Prognostic_studies Limits: Animals Language: En Journal: Biomed Chromatogr Year: 2020 Type: Article Affiliation country: China

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