Influenza A virus infection induces indoleamine 2,3-dioxygenase (IDO) expression and modulates subsequent inflammatory mediators in nasal epithelial cells.

Lin, Yi-Tsen; Lin, Chih-Feng; Yeh, Te-Huei

Lin, Yi-Tsen; Lin, Chih-Feng; Yeh, Te-Huei.

Affiliation

Lin YT; Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan.
Lin CF; Graduate School of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
Yeh TH; Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan.

Acta Otolaryngol ; 140(2): 149-156, 2020 Feb.

Article in En | MEDLINE | ID: mdl-31852346

Subject(s)

Cytokines/metabolism; Host-Pathogen Interactions; Indoleamine-Pyrrole 2,3,-Dioxygenase/metabolism; Influenza, Human/metabolism; Nasal Mucosa/metabolism; A549 Cells; Epithelial Cells/metabolism; Humans; Influenza A virus/physiology; Primary Cell Culture; Tryptophan/metabolism

Key words

IDO; Nasal epithelial cells; influenza virus; innate immunity; kynurenine; tryptophan

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytokines / Indoleamine-Pyrrole 2,3,-Dioxygenase / Influenza, Human / Host-Pathogen Interactions / Nasal Mucosa Limits: Humans Language: En Journal: Acta Otolaryngol Year: 2020 Type: Article Affiliation country: Taiwan

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