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Ferulin C triggers potent PAK1 and p21-mediated anti-tumor effects in breast cancer by inhibiting Tubulin polymerization in vitro and in vivo.
Yao, Dahong; Pan, Dabo; Zhen, Yongqi; Huang, Jian; Wang, Jinhui; Zhang, Jin; He, Zhendan.
Affiliation
  • Yao D; School of Pharmaceutical Sciences, Guangdong Key Laboratory for Genome Stability & Human Disease Prevention, Shenzhen Key Laboratory of Novel Natural Health Care Products, Innovation Platform for Natural small molecule Drugs, Engineering Laboratory of Shenzhen Natural small molecule Innovative D
  • Pan D; Institute of Traditional Chinese Medicine & Natural Products, and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University, Guangzhou, 510632, China. Electronic address: pandb17@jnu.edu.cn.
  • Zhen Y; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China. Electronic address: simplezyq@gmail.com.
  • Huang J; Shenzhen Honghui Bio-Pharmaceutical Co. Ltd., Shenzhen, 518118, China; College of Pharmacy, Harbin Medical University, Harbin, 150081, China. Electronic address: huangjian@hrbmu.edu.
  • Wang J; Shenzhen Honghui Bio-Pharmaceutical Co. Ltd., Shenzhen, 518118, China; College of Pharmacy, Harbin Medical University, Harbin, 150081, China. Electronic address: wangjinhui@hrbmu.edu.cn.
  • Zhang J; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China. Electronic address: jinjinlovemama@163.com.
  • He Z; School of Pharmaceutical Sciences, Guangdong Key Laboratory for Genome Stability & Human Disease Prevention, Shenzhen Key Laboratory of Novel Natural Health Care Products, Innovation Platform for Natural small molecule Drugs, Engineering Laboratory of Shenzhen Natural small molecule Innovative D
Pharmacol Res ; 152: 104605, 2020 02.
Article in En | MEDLINE | ID: mdl-31863866
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sesquiterpenes / Tubulin / Coumarins / Tubulin Modulators / Mammary Neoplasms, Experimental / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Pharmacol Res Journal subject: FARMACOLOGIA Year: 2020 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sesquiterpenes / Tubulin / Coumarins / Tubulin Modulators / Mammary Neoplasms, Experimental / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Pharmacol Res Journal subject: FARMACOLOGIA Year: 2020 Type: Article