Is Somatostatin Receptor and Dopamine Receptor profiling useful in the management of silent somatotroph tumors?

Martínez-López, S; García-Martínez, A; Torregrosa-Quesada, M E; López-Muñoz, B; Cámara, R; Fajardo, C; Lamas, C; Picó, A

Martínez-López, S; García-Martínez, A; Torregrosa-Quesada, M E; López-Muñoz, B; Cámara, R; Fajardo, C; Lamas, C; Picó, A.

Affiliation

Martínez-López S; Research Laboratory, Alicante General University Hospital-ISABIAL, Alicante, Spain.
García-Martínez A; Research Laboratory, Alicante General University Hospital-ISABIAL, Alicante, Spain.
Torregrosa-Quesada ME; Biochemical Analysis Department, Alicante General University Hospital, Alicante, Spain.
López-Muñoz B; Endocrinology Department, Alicante General University Hospital, Alicante, Spain.
Cámara R; Endocrinology Department, La Fe Polytechnic and University Hospital, Valencia, Spain.
Fajardo C; Endocrinology Department, La Ribera University Hospital, Alzira, Valencia, Spain.
Lamas C; Endocrinology Department, Albacete University Hospital Complex, Albacete, Spain.
Picó A; Endocrinology Department, Alicante General University Hospital-ISABIAL, Miguel Hernández University, Calle Pintor Baeza, 12, 03010, Alicante, Spain. antonio.pico@umh.es.

J Endocrinol Invest ; 43(6): 859-863, 2020 Jun.

Article in En | MEDLINE | ID: mdl-31898311

Subject(s)

Adenoma/metabolism; Neuroendocrine Tumors/metabolism; Pituitary Neoplasms/metabolism; Receptors, Dopamine D2/biosynthesis; Receptors, Somatostatin/biosynthesis; Somatotrophs/metabolism; Adenoma/diagnosis; Adenoma/genetics; Adult; Biomarkers, Tumor/biosynthesis; Biomarkers, Tumor/genetics; Disease Management; Female; Gene Expression Profiling/methods; Humans; Male; Middle Aged; Neuroendocrine Tumors/diagnosis; Neuroendocrine Tumors/genetics; Pituitary Neoplasms/diagnosis; Pituitary Neoplasms/genetics; Receptors, Dopamine D2/genetics; Receptors, Somatostatin/genetics; Somatotrophs/pathology

Key words

Acromegaly; Dopamine receptor (DRD); Pituitary neuroendocrine tumor (PitNET); Silent somatotroph tumor (sST); Somatostatin analogues (SSAs); Somatostatin receptor (SSTR)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pituitary Neoplasms / Adenoma / Receptors, Somatostatin / Receptors, Dopamine D2 / Neuroendocrine Tumors / Somatotrophs Type of study: Diagnostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: J Endocrinol Invest Year: 2020 Type: Article Affiliation country: Spain

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