Management of toxicity to isoform &#945;-specific PI3K inhibitors.

Nunnery, S E; Mayer, I A

Management of toxicity to isoform α-specific PI3K inhibitors.

Nunnery, S E; Mayer, I A.

Affiliation

Nunnery SE; Division of Hematology/Oncology, Department of Medicine, Vanderbilt-Ingram Cancer Center (VICC), Vanderbilt University Medical Center, Nashville, USA.
Mayer IA; Division of Hematology/Oncology, Department of Medicine, Vanderbilt-Ingram Cancer Center (VICC), Vanderbilt University Medical Center, Nashville, USA. Electronic address: Ingrid.mayer@vumc.org.

Ann Oncol ; 30 Suppl 10: x21-x26, 2019 12.

Article in En | MEDLINE | ID: mdl-31928691

Subject(s)

Breast Neoplasms/drug therapy; Phosphoinositide-3 Kinase Inhibitors/adverse effects; Protein Kinase Inhibitors/adverse effects; Transcription Factors/antagonists & inhibitors; Breast Neoplasms/metabolism; Breast Neoplasms/pathology; Disease Management; Drug-Related Side Effects and Adverse Reactions/therapy; Female; Humans; Phosphoinositide-3 Kinase Inhibitors/pharmacology; Phosphoinositide-3 Kinase Inhibitors/therapeutic use; Protein Kinase Inhibitors/pharmacology; Protein Kinase Inhibitors/therapeutic use; Proto-Oncogene Proteins c-akt/metabolism; Randomized Controlled Trials as Topic; Signal Transduction/drug effects; Withholding Treatment

Key words

PI3K inhibitors; supportive care; toxicities

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Breast Neoplasms / Protein Kinase Inhibitors / Phosphoinositide-3 Kinase Inhibitors Type of study: Clinical_trials Limits: Female / Humans Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2019 Type: Article Affiliation country: United States

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