Friedreich Ataxia/genetics; Iron-Sulfur Proteins/genetics; Mitochondria/genetics; Mitochondrial Diseases/genetics; Mitochondrial Proteins/genetics; Molecular Chaperones/genetics; ATP-Binding Cassette Transporters/chemistry; ATP-Binding Cassette Transporters/genetics; ATP-Binding Cassette Transporters/metabolism; Carbon-Sulfur Lyases/chemistry; Carbon-Sulfur Lyases/genetics; Carbon-Sulfur Lyases/metabolism; Ferredoxins/chemistry; Ferredoxins/genetics; Ferredoxins/metabolism; Friedreich Ataxia/metabolism; Friedreich Ataxia/pathology; Gene Expression Regulation; Glutaredoxins/chemistry; Glutaredoxins/genetics; Glutaredoxins/metabolism; Humans; Iron-Binding Proteins/chemistry; Iron-Binding Proteins/genetics; Iron-Binding Proteins/metabolism; Iron-Sulfur Proteins/chemistry; Iron-Sulfur Proteins/metabolism; Mitochondria/metabolism; Mitochondria/pathology; Mitochondrial Diseases/metabolism; Mitochondrial Diseases/pathology; Mitochondrial Proteins/chemistry; Mitochondrial Proteins/metabolism; Models, Molecular; Molecular Chaperones/chemistry; Molecular Chaperones/metabolism; Protein Biosynthesis; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Saccharomyces cerevisiae/genetics; Saccharomyces cerevisiae/metabolism; Frataxin

ABC protein; CIA machinery; FRDA; Fe/S cluster; Fe/S disease; Friedrich's ataxia; ISC machinery; MMDS; cysteine desulfurase; cytosolic iron-sulfur protein assembly machinery; ferredoxin; frataxin; glutaredoxin; iron-sulfur cluster assembly machinery; multiple mitochondrial dysfunction syndromes