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Lymphocyte DNA methylation mediates genetic risk at shared immune-mediated disease loci.
Clark, Alexander D; Nair, Nisha; Anderson, Amy E; Thalayasingam, Nishanthi; Naamane, Najib; Skelton, Andrew J; Diboll, Julie; Barton, Anne; Eyre, Stephen; Isaacs, John D; Pratt, Arthur G; Reynard, Louise N.
Affiliation
  • Clark AD; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, United Kingdom.
  • Nair N; Versus Arthritis Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester Manchester, United Kingdom; NIHR Manchester Musculoskeletal BRC, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
  • Anderson AE; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, United Kingdom.
  • Thalayasingam N; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, United Kingdom.
  • Naamane N; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, United Kingdom.
  • Skelton AJ; Bioinformatics Support Unit, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Diboll J; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, United Kingdom.
  • Barton A; Versus Arthritis Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester Manchester, United Kingdom; NIHR Manchester Musculoskeletal BRC, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
  • Eyre S; Versus Arthritis Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester Manchester, United Kingdom; NIHR Manchester Musculoskeletal BRC, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
  • Isaacs JD; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, United Kingdom; Musculoskeletal Services Directorate, Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, United Kingdom.
  • Pratt AG; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, United Kingdom; Musculoskeletal Services Directorate, Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, United Kingdom. Electronic address: arthur.pratt@ncl.ac.uk.
  • Reynard LN; Newcastle University Biosciences Institute, Newcastle upon Tyne, United Kingdom.
J Allergy Clin Immunol ; 145(5): 1438-1451, 2020 05.
Article in En | MEDLINE | ID: mdl-31945409
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / B-Lymphocytes / CD4-Positive T-Lymphocytes / DNA Methylation / Genetic Predisposition to Disease Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: J Allergy Clin Immunol Year: 2020 Type: Article Affiliation country: United kingdom
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / B-Lymphocytes / CD4-Positive T-Lymphocytes / DNA Methylation / Genetic Predisposition to Disease Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: J Allergy Clin Immunol Year: 2020 Type: Article Affiliation country: United kingdom