G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody.

Bhudia, Nisha; Desai, Sapna; King, Natalie; Ancellin, Nicolas; Grillot, Didier; Barnes, Ashley A; Dowell, Simon J

Bhudia, Nisha; Desai, Sapna; King, Natalie; Ancellin, Nicolas; Grillot, Didier; Barnes, Ashley A; Dowell, Simon J.

Affiliation

Bhudia N; Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK.
Desai S; Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK.
King N; Excelya Clinical Research, Boulogne-Billancourt, France.
Ancellin N; Oncodesign, Villebon-Sur-Yvette, France.
Grillot D; Oncodesign, Villebon-Sur-Yvette, France.
Barnes AA; Censo Biotechnologies Ltd., Babraham, UK.
Dowell SJ; Medicinal Science and Technology, GlaxoSmithKline, Stevenage, UK. simon.j.dowell@gsk.com.

Sci Rep ; 10(1): 1004, 2020 01 22.

Article in En | MEDLINE | ID: mdl-31969668

Subject(s)

Antibodies/immunology; Antigens, CD/metabolism; GTP-Binding Proteins/metabolism; Receptors, G-Protein-Coupled/metabolism; Signal Transduction; Blotting, Western; HEK293 Cells/metabolism; Humans; Immunoprecipitation; Receptors, G-Protein-Coupled/antagonists & inhibitors; Receptors, G-Protein-Coupled/immunology; Signal Transduction/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Antigens, CD / GTP-Binding Proteins / Receptors, G-Protein-Coupled / Antibodies Limits: Humans Language: En Journal: Sci Rep Year: 2020 Type: Article Affiliation country: United kingdom

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