Knockdown of otubain 2 inhibits liver cancer cell growth by suppressing NF-&#954;B signaling.

Gu, Zhen-Lin; Huang, Jing; Zhen, Lin-Lin

Knockdown of otubain 2 inhibits liver cancer cell growth by suppressing NF-κB signaling.

Gu, Zhen-Lin; Huang, Jing; Zhen, Lin-Lin.

Affiliation

Gu ZL; Department of Interventional Radiology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huaian, Jiangsu, China.
Huang J; Department of Radiation Oncology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huaian, Jiangsu, China.
Zhen LL; Department of Breast and Thyroid Surgery, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huaian, Jiangsu, China.

Kaohsiung J Med Sci ; 36(6): 399-404, 2020 Jun.

Article in En | MEDLINE | ID: mdl-32003539

Subject(s)

Carcinogenesis/genetics; Carcinoma, Hepatocellular/genetics; Hepatoblastoma/genetics; Liver Neoplasms/genetics; Thiolester Hydrolases/genetics; Transcription Factor RelA/genetics; Carcinogenesis/metabolism; Carcinogenesis/pathology; Carcinoma, Hepatocellular/metabolism; Carcinoma, Hepatocellular/mortality; Carcinoma, Hepatocellular/pathology; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Genes, Reporter; Hepatoblastoma/metabolism; Hepatoblastoma/mortality; Hepatoblastoma/pathology; Humans; Liver Neoplasms/metabolism; Liver Neoplasms/mortality; Liver Neoplasms/pathology; Luciferases/genetics; Luciferases/metabolism; Phenyl Ethers/pharmacology; Phenylenediamines/pharmacology; Phosphorylation/drug effects; Quinazolines/pharmacology; RNA, Small Interfering/genetics; RNA, Small Interfering/metabolism; Signal Transduction; Survival Analysis; Thiolester Hydrolases/antagonists & inhibitors; Thiolester Hydrolases/metabolism; Transcription Factor RelA/antagonists & inhibitors; Transcription Factor RelA/metabolism

Key words

NF-κB; OTUB2; cell growth; liver cancer; target

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiolester Hydrolases / Hepatoblastoma / Carcinoma, Hepatocellular / Transcription Factor RelA / Carcinogenesis / Liver Neoplasms Language: En Journal: Kaohsiung J Med Sci Journal subject: MEDICINA Year: 2020 Type: Article Affiliation country: China

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