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Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex Structures.
Hua, Tian; Li, Xiaoting; Wu, Lijie; Iliopoulos-Tsoutsouvas, Christos; Wang, Yuxia; Wu, Meng; Shen, Ling; Brust, Christina A; Nikas, Spyros P; Song, Feng; Song, Xiyong; Yuan, Shuguang; Sun, Qianqian; Wu, Yiran; Jiang, Shan; Grim, Travis W; Benchama, Othman; Stahl, Edward L; Zvonok, Nikolai; Zhao, Suwen; Bohn, Laura M; Makriyannis, Alexandros; Liu, Zhi-Jie.
Affiliation
  • Hua T; iHuman Institute, ShanghaiTech University, Shanghai 201210, China. Electronic address: huatian@shanghaitech.edu.cn.
  • Li X; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.
  • Wu L; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.
  • Iliopoulos-Tsoutsouvas C; Center for Drug Discovery and Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA.
  • Wang Y; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.
  • Wu M; iHuman Institute, ShanghaiTech University, Shanghai 201210, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
  • Shen L; iHuman Institute, ShanghaiTech University, Shanghai 201210, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
  • Brust CA; Departments of Molecular Medicine and Neuroscience, Scripps Research, Jupiter, FL 33458, USA.
  • Nikas SP; Center for Drug Discovery and Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA.
  • Song F; School of Life Science, Dezhou University, Dezhou 253023, Shandong Province, China.
  • Song X; Institute of Molecular and Clinical Medicine, Kunming Medical University, Kunming 650500, Yunnan Province, China.
  • Yuan S; The Research Center for Computer-aided Drug Discovery, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
  • Sun Q; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.
  • Wu Y; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.
  • Jiang S; Center for Drug Discovery and Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA.
  • Grim TW; Departments of Molecular Medicine and Neuroscience, Scripps Research, Jupiter, FL 33458, USA.
  • Benchama O; Center for Drug Discovery and Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA.
  • Stahl EL; Departments of Molecular Medicine and Neuroscience, Scripps Research, Jupiter, FL 33458, USA.
  • Zvonok N; Center for Drug Discovery and Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA.
  • Zhao S; iHuman Institute, ShanghaiTech University, Shanghai 201210, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
  • Bohn LM; Departments of Molecular Medicine and Neuroscience, Scripps Research, Jupiter, FL 33458, USA.
  • Makriyannis A; Center for Drug Discovery and Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA; Center for Drug Discovery and Departments of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA.
  • Liu ZJ; iHuman Institute, ShanghaiTech University, Shanghai 201210, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China; Institute of Molecular and Clinical Medicine, Kunming Medical University, Kunming 650500, Yunnan Province, China. Electronic address: liuzhj@shan
Cell ; 180(4): 655-665.e18, 2020 02 20.
Article in En | MEDLINE | ID: mdl-32004463
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / GTP-Binding Protein alpha Subunits, Gi-Go / Receptor, Cannabinoid, CB1 / Receptor, Cannabinoid, CB2 / Cannabinoid Receptor Agonists Limits: Animals / Humans Language: En Journal: Cell Year: 2020 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / GTP-Binding Protein alpha Subunits, Gi-Go / Receptor, Cannabinoid, CB1 / Receptor, Cannabinoid, CB2 / Cannabinoid Receptor Agonists Limits: Animals / Humans Language: En Journal: Cell Year: 2020 Type: Article