Influence of corticosteroid therapy on viral reactivation in drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms.

Tohyama, Mikiko; Hashimoto, Koji; Oda, Fumiko; Namba, Chika; Sayama, Koji

Tohyama, Mikiko; Hashimoto, Koji; Oda, Fumiko; Namba, Chika; Sayama, Koji.

Affiliation

Tohyama M; Department of Dermatology, National Hospital Organization Shikoku Cancer Center, Matsuyama, 791-0280, Japan.
Hashimoto K; Department of Dermatology, Ehime University Graduate School of Medicine, Toon, 791-0295, Japan.
Oda F; Department of Dermatology, Ehime University Graduate School of Medicine, Toon, 791-0295, Japan.
Namba C; Department of Dermatology, Ehime University Graduate School of Medicine, Toon, 791-0295, Japan.
Sayama K; Department of Dermatology, Ehime University Graduate School of Medicine, Toon, 791-0295, Japan.

J Dermatol ; 47(5): 476-482, 2020 May.

Article in En | MEDLINE | ID: mdl-32162382

Subject(s)

Drug Hypersensitivity Syndrome/drug therapy; Glucocorticoids/adverse effects; Herpesviridae Infections/diagnosis; Immunosuppressive Agents/adverse effects; Virus Activation/drug effects; Adult; Aged; Aged, 80 and over; Cytomegalovirus/genetics; Cytomegalovirus/immunology; Cytomegalovirus/isolation & purification; DNA, Viral/isolation & purification; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Hypersensitivity Syndrome/complications; Drug Hypersensitivity Syndrome/diagnosis; Drug Hypersensitivity Syndrome/immunology; Female; Glucocorticoids/administration & dosage; Herpesviridae Infections/blood; Herpesviridae Infections/immunology; Herpesviridae Infections/virology; Herpesvirus 4, Human/genetics; Herpesvirus 4, Human/immunology; Herpesvirus 4, Human/isolation & purification; Herpesvirus 6, Human/genetics; Herpesvirus 6, Human/immunology; Herpesvirus 6, Human/isolation & purification; Humans; Immunosuppressive Agents/administration & dosage; Male; Middle Aged; Severity of Illness Index; Virus Activation/immunology; Young Adult

Key words

cytomegalovirus; drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms; human herpesvirus 6; soluble interleukin-2 receptor; systemic corticosteroid

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Virus Activation / Herpesviridae Infections / Drug Hypersensitivity Syndrome / Glucocorticoids / Immunosuppressive Agents Type of study: Diagnostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: J Dermatol Year: 2020 Type: Article Affiliation country: Japan

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