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Orthotopic tongue squamous cell carcinoma (SCC) model exhibiting a different tumor-infiltrating T-cell status with margin-restricted CD8+ T cells and regulatory T cell-dominance, compared to skin SCC.
Kashima, Yoshihisa; Nishii, Naoto; Tachinami, Hidetake; Furusawa, Emi; Nagai, Shigenori; Harada, Hiroyuki; Azuma, Miyuki.
Affiliation
  • Kashima Y; Department of Molecular Immunology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan; Department of Oral and Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
  • Nishii N; Department of Molecular Immunology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan; Department of Oral and Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
  • Tachinami H; Department of Molecular Immunology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
  • Furusawa E; Department of Molecular Immunology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
  • Nagai S; Department of Molecular Immunology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
  • Harada H; Department of Oral and Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
  • Azuma M; Department of Molecular Immunology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address: miyuki.mim@tmd.ac.jp.
Biochem Biophys Res Commun ; 526(1): 218-224, 2020 05 21.
Article in En | MEDLINE | ID: mdl-32204917
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Tongue Neoplasms / Carcinoma, Squamous Cell / Lymphocytes, Tumor-Infiltrating / T-Lymphocytes, Regulatory / CD8-Positive T-Lymphocytes Type of study: Prognostic_studies Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 2020 Type: Article Affiliation country: Japan
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Tongue Neoplasms / Carcinoma, Squamous Cell / Lymphocytes, Tumor-Infiltrating / T-Lymphocytes, Regulatory / CD8-Positive T-Lymphocytes Type of study: Prognostic_studies Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 2020 Type: Article Affiliation country: Japan