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Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients.
Nakayama, Akiyoshi; Nakatochi, Masahiro; Kawamura, Yusuke; Yamamoto, Ken; Nakaoka, Hirofumi; Shimizu, Seiko; Higashino, Toshihide; Koyama, Teruhide; Hishida, Asahi; Kuriki, Kiyonori; Watanabe, Miki; Shimizu, Toru; Ooyama, Keiko; Ooyama, Hiroshi; Nagase, Mitsuo; Hidaka, Yuji; Matsui, Daisuke; Tamura, Takashi; Nishiyama, Takeshi; Shimanoe, Chisato; Katsuura-Kamano, Sakurako; Takashima, Naoyuki; Shirai, Yuya; Kawaguchi, Makoto; Takao, Mikiya; Sugiyama, Ryo; Takada, Yuzo; Nakamura, Takahiro; Nakashima, Hiroshi; Tsunoda, Masashi; Danjoh, Inaho; Hozawa, Atsushi; Hosomichi, Kazuyoshi; Toyoda, Yu; Kubota, Yu; Takada, Tappei; Suzuki, Hiroshi; Stiburkova, Blanka; Major, Tanya J; Merriman, Tony R; Kuriyama, Nagato; Mikami, Haruo; Takezaki, Toshiro; Matsuo, Keitaro; Suzuki, Sadao; Hosoya, Tatsuo; Kamatani, Yoichiro; Kubo, Michiaki; Ichida, Kimiyoshi; Wakai, Kenji.
Affiliation
  • Nakayama A; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan.
  • Nakatochi M; Medical Squadron, Air Base Group, Western Aircraft Control and Warning Wing, Japan Air Self-Defense Force, Kasuga, Japan.
  • Kawamura Y; Division of Department of Nursing, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Yamamoto K; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan.
  • Nakaoka H; Department of General Medicine, National Defense Medical College, Tokorozawa, Japan.
  • Shimizu S; Department of Medical Biochemistry, Kurume University School of Medicine, Kurume, Japan.
  • Higashino T; Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Mishima, Japan.
  • Koyama T; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan.
  • Hishida A; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan.
  • Kuriki K; Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Japan.
  • Watanabe M; Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Shimizu T; Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Ooyama K; Laboratory of Public Health, School of Food and Nutritional Sciences, University of Shizuoka, Shizuoka, Japan.
  • Ooyama H; Department of Public Health, Nagoya City University Graduate School Medical Science, Nagoya, Japan.
  • Nagase M; Midorigaoka Hospital, Takatsuki, Japan.
  • Hidaka Y; Kyoto Industrial Health Association, Kyoto, Japan.
  • Matsui D; Ryougoku East Gate Clinic, Tokyo, Japan.
  • Tamura T; Ryougoku East Gate Clinic, Tokyo, Japan.
  • Nishiyama T; Nagase Clinic, Tokyo, Japan.
  • Shimanoe C; Akasaka Central Clinic, Tokyo, Japan.
  • Katsuura-Kamano S; Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Takashima N; Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Shirai Y; Department of Public Health, Nagoya City University Graduate School Medical Science, Nagoya, Japan.
  • Kawaguchi M; Department of Preventive Medicine, Faculty of Medicine, Saga University, Saga, Japan.
  • Takao M; Clinical Research Center, Saga University Hospital, Saga, Japan.
  • Sugiyama R; Department of Preventive Medicine, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
  • Takada Y; Department of Health Science, Shiga University of Medical Science, Otsu, Japan.
  • Nakamura T; Department of Public Health, Faculty of Medicine, Kindai University, Osaka-Sayama, Japan.
  • Nakashima H; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
  • Tsunoda M; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.
  • Danjoh I; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan.
  • Hozawa A; Department of Urology, National Defense Medical College, Tokorozawa, Japan.
  • Hosomichi K; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan.
  • Toyoda Y; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
  • Kubota Y; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan.
  • Takada T; Faculty of Medical Science, Teikyo University of Science, Tokyo, Japan.
  • Suzuki H; Laboratory for Mathematics, National Defense Medical College, Tokorozawa, Japan.
  • Stiburkova B; Department of Preventive Medicine and Public Health, National Defense Medical College, Tokorozawa, Japan.
  • Major TJ; Department of Preventive Medicine and Public Health, National Defense Medical College, Tokorozawa, Japan.
  • Merriman TR; Group of Privacy Controls, Tohoku Medical Megabank Organization, Sendai, Japan.
  • Kuriyama N; Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
  • Mikami H; Department of Bioinformatics and Genomics, Graduate School of Advanced Preventive Medical Sciences, Kanazawa University, Kanazawa, Japan.
  • Takezaki T; Department of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan.
  • Matsuo K; Department of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan.
  • Suzuki S; Department of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan.
  • Hosoya T; Department of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan.
  • Kamatani Y; Department of Pediatrics and Adolescent Medicine, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
  • Kubo M; Institute of Rheumatology, Prague, Czech Republic.
  • Ichida K; Department of Biochemisty, University of Otago, Dunedin, New Zealand.
  • Wakai K; Department of Biochemisty, University of Otago, Dunedin, New Zealand.
Ann Rheum Dis ; 79(5): 657-665, 2020 05.
Article in En | MEDLINE | ID: mdl-32238385
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Predisposition to Disease / Genome-Wide Association Study / Aldehyde Dehydrogenase, Mitochondrial / ATP Binding Cassette Transporter, Subfamily G, Member 2 / Gout / Neoplasm Proteins Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Humans / Male Country/Region as subject: Asia Language: En Journal: Ann Rheum Dis Year: 2020 Type: Article Affiliation country: Japan
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Predisposition to Disease / Genome-Wide Association Study / Aldehyde Dehydrogenase, Mitochondrial / ATP Binding Cassette Transporter, Subfamily G, Member 2 / Gout / Neoplasm Proteins Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Humans / Male Country/Region as subject: Asia Language: En Journal: Ann Rheum Dis Year: 2020 Type: Article Affiliation country: Japan