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Impacts of CYP2C19 genetic polymorphisms on bioavailability and effect on platelet adhesion of vicagrel, a novel thienopyridine P2Y12 inhibitor.
Zhang, Yifan; Zhu, Xiaoxue; Zhan, Yan; Li, Xiaojiao; Liu, Cai; Zhu, Yunting; Zhang, Hong; Wei, Haijing; Xia, Yu; Sun, Hongbin; Liu, Yongqiang; Lai, Xiaojuan; Gong, Yanchun; Liu, Xuefang; Li, Yongguo; Ding, Yanhua; Zhong, Dafang.
Affiliation
  • Zhang Y; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Zhu X; Phase I Clinical Trial Unit, First Hospital, Jilin University, Jilin, China.
  • Zhan Y; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Li X; Phase I Clinical Trial Unit, First Hospital, Jilin University, Jilin, China.
  • Liu C; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Zhu Y; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Zhang H; Phase I Clinical Trial Unit, First Hospital, Jilin University, Jilin, China.
  • Wei H; Phase I Clinical Trial Unit, First Hospital, Jilin University, Jilin, China.
  • Xia Y; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Sun H; State Key Laboratory of Natural Medicines and Center of Drug Discovery, College of Pharmacy, China Pharmaceutical University, Nanjing, China.
  • Liu Y; Jiangsu Vcare PharmaTech Co., Ltd., Nanjing, China.
  • Lai X; Jiangsu Vcare PharmaTech Co., Ltd., Nanjing, China.
  • Gong Y; Jiangsu Vcare PharmaTech Co., Ltd., Nanjing, China.
  • Liu X; Jiangsu Vcare PharmaTech Co., Ltd., Nanjing, China.
  • Li Y; Hua Medicine Ltd., Shanghai, China.
  • Ding Y; Phase I Clinical Trial Unit, First Hospital, Jilin University, Jilin, China.
  • Zhong D; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Br J Clin Pharmacol ; 86(9): 1860-1874, 2020 09.
Article in En | MEDLINE | ID: mdl-32267573
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenylacetates / Thiophenes / Cytochrome P-450 CYP2C19 Type of study: Clinical_trials Limits: Female / Humans / Male Language: En Journal: Br J Clin Pharmacol Year: 2020 Type: Article Affiliation country: China
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenylacetates / Thiophenes / Cytochrome P-450 CYP2C19 Type of study: Clinical_trials Limits: Female / Humans / Male Language: En Journal: Br J Clin Pharmacol Year: 2020 Type: Article Affiliation country: China