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Practical synthesis of peptide C-terminal aldehyde on a solid support.
Konno, Hiroyuki; Sema, Yoshihiro; Ishii, Manabu; Hattori, Yasunao; Nosaka, Kazuto; Akaji, Kenichi.
Affiliation
  • Konno H; Department of Biochemical Engineering, Graduate School of Science and Technology, Yamagata University, Yonezawa, Yamagata 992-8510, Japan.
  • Sema Y; Department of Biochemical Engineering, Graduate School of Science and Technology, Yamagata University, Yonezawa, Yamagata 992-8510, Japan.
  • Ishii M; Department of Biochemical Engineering, Graduate School of Science and Technology, Yamagata University, Yonezawa, Yamagata 992-8510, Japan.
  • Hattori Y; Department of Medicinal Chemistry, Kyoto Pharmaceutical University, Yamashina-ku, Kyoto 607-8414, Japan.
  • Nosaka K; Department of Chemistry, Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan.
  • Akaji K; Department of Medicinal Chemistry, Kyoto Pharmaceutical University, Yamashina-ku, Kyoto 607-8414, Japan.
Tetrahedron Lett ; 54(36): 4848-4850, 2013 Sep 04.
Article in En | MEDLINE | ID: mdl-32287443
ABSTRACT
We have investigated practical synthetic routes for the preparation of peptide aldehyde on a solid support. Peptide aldehyde was synthesized via efficient transformation of acetal/thioacetal structures.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Tetrahedron Lett Year: 2013 Type: Article Affiliation country: Japan

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Tetrahedron Lett Year: 2013 Type: Article Affiliation country: Japan