Dysregulated signalling pathways in innate immune cells with cystic fibrosis mutations.

Lara-Reyna, Samuel; Holbrook, Jonathan; Jarosz-Griffiths, Heledd H; Peckham, Daniel; McDermott, Michael F

Lara-Reyna, Samuel; Holbrook, Jonathan; Jarosz-Griffiths, Heledd H; Peckham, Daniel; McDermott, Michael F.

Affiliation

Lara-Reyna S; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, LS9 7TF, UK. umsjlr@leeds.ac.uk.
Holbrook J; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, LS9 7TF, UK. umsjlr@leeds.ac.uk.
Jarosz-Griffiths HH; Leeds Cystic Fibrosis Trust Strategic Research Centre, University of Leeds, Leeds, LS9 7TF, UK. umsjlr@leeds.ac.uk.
Peckham D; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, LS9 7TF, UK.
McDermott MF; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, LS9 7TF, UK.

Cell Mol Life Sci ; 77(22): 4485-4503, 2020 Nov.

Article in En | MEDLINE | ID: mdl-32367193

Subject(s)

Cystic Fibrosis/genetics; Cystic Fibrosis/immunology; Immunity, Innate/genetics; Immunity, Innate/immunology; Mutation/genetics; Signal Transduction/genetics; Signal Transduction/immunology; Animals; Cystic Fibrosis Transmembrane Conductance Regulator/genetics; Cystic Fibrosis Transmembrane Conductance Regulator/immunology; Humans; Mutation/immunology

Key words

CFTR and autoinflammation; Cystic fibrosis; Inflammation; Macrophages; Monocytes; Neutrophils

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Cystic Fibrosis / Immunity, Innate / Mutation Limits: Animals / Humans Language: En Journal: Cell Mol Life Sci Journal subject: BIOLOGIA MOLECULAR Year: 2020 Type: Article Affiliation country: United kingdom

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