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Efficacy and safety of anti-CD45-saporin as conditioning agent for RAG deficiency.
Castiello, Maria Carmina; Bosticardo, Marita; Sacchetti, Nicolò; Calzoni, Enrica; Fontana, Elena; Yamazaki, Yasuhiro; Draghici, Elena; Corsino, Cristina; Bortolomai, Ileana; Sereni, Lucia; Yu, Hsin-Hui; Uva, Paolo; Palchaudhuri, Rahul; Scadden, David T; Villa, Anna; Notarangelo, Luigi D.
Affiliation
  • Castiello MC; San Raffaele Telethon Institute for Gene Therapy SR-Tiget, IRCCS San Raffaele Scientific Institute, Milan, Cagliari, Italy; Institute of Genetic and Biomedical Research Milan Unit, National Research Council, Milan, Cagliari, Italy.
  • Bosticardo M; Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
  • Sacchetti N; San Raffaele Telethon Institute for Gene Therapy SR-Tiget, IRCCS San Raffaele Scientific Institute, Milan, Cagliari, Italy.
  • Calzoni E; San Raffaele Telethon Institute for Gene Therapy SR-Tiget, IRCCS San Raffaele Scientific Institute, Milan, Cagliari, Italy; Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethe
  • Fontana E; Institute of Genetic and Biomedical Research Milan Unit, National Research Council, Milan, Cagliari, Italy; Human Genome Lab, Humanitas Clinical and Research Center, Milan, Cagliari, Italy.
  • Yamazaki Y; Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
  • Draghici E; San Raffaele Telethon Institute for Gene Therapy SR-Tiget, IRCCS San Raffaele Scientific Institute, Milan, Cagliari, Italy.
  • Corsino C; Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
  • Bortolomai I; San Raffaele Telethon Institute for Gene Therapy SR-Tiget, IRCCS San Raffaele Scientific Institute, Milan, Cagliari, Italy.
  • Sereni L; San Raffaele Telethon Institute for Gene Therapy SR-Tiget, IRCCS San Raffaele Scientific Institute, Milan, Cagliari, Italy.
  • Yu HH; Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
  • Uva P; CRS4, Science and Technology Park Polaris, Pula, Cagliari, Italy.
  • Palchaudhuri R; Department of Stem Cell and Regenerative Biology, Harvard University, Harvard Stem Cell Institute, Cambridge, Mass; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Mass; Magenta Therapeutics, Cambridge, Mass.
  • Scadden DT; Department of Stem Cell and Regenerative Biology, Harvard University, Harvard Stem Cell Institute, Cambridge, Mass; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Mass.
  • Villa A; San Raffaele Telethon Institute for Gene Therapy SR-Tiget, IRCCS San Raffaele Scientific Institute, Milan, Cagliari, Italy; Institute of Genetic and Biomedical Research Milan Unit, National Research Council, Milan, Cagliari, Italy. Electronic address: villa.anna@hsr.it.
  • Notarangelo LD; Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md. Electronic address: luigi.notarangelo2@nih.gov.
J Allergy Clin Immunol ; 147(1): 309-320.e6, 2021 01.
Article in En | MEDLINE | ID: mdl-32387109
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow Transplantation / Severe Combined Immunodeficiency / Leukocyte Common Antigens / Immunoconjugates / Homeodomain Proteins / Transplantation Conditioning / Saporins / Antibodies, Monoclonal Limits: Animals Language: En Journal: J Allergy Clin Immunol Year: 2021 Type: Article Affiliation country: Italy
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow Transplantation / Severe Combined Immunodeficiency / Leukocyte Common Antigens / Immunoconjugates / Homeodomain Proteins / Transplantation Conditioning / Saporins / Antibodies, Monoclonal Limits: Animals Language: En Journal: J Allergy Clin Immunol Year: 2021 Type: Article Affiliation country: Italy