Tocilizumab therapy reduced intensive care unit admissions and/or mortality in COVID-19 patients.

Klopfenstein, T; Zayet, S; Lohse, A; Balblanc, J-C; Badie, J; Royer, P-Y; Toko, L; Mezher, C; Kadiane-Oussou, N J; Bossert, M; Bozgan, A-M; Charpentier, A; Roux, M-F; Contreras, R; Mazurier, I; Dussert, P; Gendrin, V; Conrozier, T

Klopfenstein, T; Zayet, S; Lohse, A; Balblanc, J-C; Badie, J; Royer, P-Y; Toko, L; Mezher, C; Kadiane-Oussou, N J; Bossert, M; Bozgan, A-M; Charpentier, A; Roux, M-F; Contreras, R; Mazurier, I; Dussert, P; Gendrin, V; Conrozier, T.

Affiliation

Klopfenstein T; Infectious Disease Department, Nord Franche-Comté Hospital, 90400 Trévenans, France. Electronic address: timothee.klopfenstein@hnfc.fr.
Zayet S; Infectious Disease Department, Nord Franche-Comté Hospital, 90400 Trévenans, France. Electronic address: souhail.zayet@gmail.com.
Lohse A; Rheumatology Department, Nord Franche-Comté Hospital, 90400 Trévenans, France.
Balblanc JC; Rheumatology Department, Nord Franche-Comté Hospital, 90400 Trévenans, France.
Badie J; Intensive Care Unit Department, Nord Franche-Comté Hospital, 90400 Trévenans, France.
Royer PY; Infectious Disease Department, Nord Franche-Comté Hospital, 90400 Trévenans, France.
Toko L; Infectious Disease Department, Nord Franche-Comté Hospital, 90400 Trévenans, France.
Mezher C; Intensive Care Unit Department, Nord Franche-Comté Hospital, 90400 Trévenans, France.
Kadiane-Oussou NJ; Infectious Disease Department, Nord Franche-Comté Hospital, 90400 Trévenans, France.
Bossert M; Rheumatology Department, Nord Franche-Comté Hospital, 90400 Trévenans, France.
Bozgan AM; Rheumatology Department, Nord Franche-Comté Hospital, 90400 Trévenans, France.
Charpentier A; Rheumatology Department, Nord Franche-Comté Hospital, 90400 Trévenans, France.
Roux MF; Pharmacology Department, Nord Franche-Comté Hospital, 90400 Trévenans, France.
Contreras R; Pharmacology Department, Nord Franche-Comté Hospital, 90400 Trévenans, France.
Mazurier I; Biological Department, Nord Franche-Comté Hospital, 90400 Trévenans, France.
Dussert P; Biological Department, Nord Franche-Comté Hospital, 90400 Trévenans, France.
Gendrin V; Infectious Disease Department, Nord Franche-Comté Hospital, 90400 Trévenans, France.
Conrozier T; Rheumatology Department, Nord Franche-Comté Hospital, 90400 Trévenans, France.

Med Mal Infect ; 50(5): 397-400, 2020 Aug.

Article in En | MEDLINE | ID: mdl-32387320

Subject(s)

Antibodies, Monoclonal, Humanized/therapeutic use; Coronavirus Infections/drug therapy; Coronavirus Infections/epidemiology; Coronavirus Infections/mortality; Intensive Care Units/statistics & numerical data; Patient Admission/statistics & numerical data; Pneumonia, Viral/drug therapy; Pneumonia, Viral/epidemiology; Pneumonia, Viral/mortality; Adolescent; Adult; Aged; Aged, 80 and over; Betacoronavirus/drug effects; Betacoronavirus/immunology; COVID-19; Case-Control Studies; Comorbidity; Coronavirus Infections/pathology; Critical Illness/epidemiology; Critical Illness/mortality; Female; France/epidemiology; Humans; Male; Middle Aged; Mortality; Pandemics; Pneumonia, Viral/pathology; Retrospective Studies; SARS-CoV-2; Severity of Illness Index; Treatment Outcome; Young Adult

Key words

COVID-19; Intensive care unit; Mortality; SARS-CoV-2; Tocilizumab

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Patient Admission / Pneumonia, Viral / Coronavirus Infections / Antibodies, Monoclonal, Humanized / Intensive Care Units Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Med Mal Infect Year: 2020 Type: Article

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