Role of nitric oxide in mediating the cardioprotective effect of agomelatine against isoproterenol-induced myocardial injury in rats.

Khalaf, Hanaa M; Abdalla, Ahlam M; Ahmed, Amira F; Abdel-Aziz, Asmaa Mohamed

Khalaf, Hanaa M; Abdalla, Ahlam M; Ahmed, Amira F; Abdel-Aziz, Asmaa Mohamed.

Affiliation

Khalaf HM; Department of Pharmacology, Faculty of Medicine, Minia University, Minia, 61511, Egypt.
Abdalla AM; Department of Biochemistry, Faculty of Medicine, Minia University, Minia, 61511, Egypt.
Ahmed AF; Department of Histology, Faculty of Medicine, Minia University, Minia, 61511, Egypt.
Abdel-Aziz AM; Department of Pharmacology, Faculty of Medicine, Minia University, Minia, 61511, Egypt. asmaaabdelaziz303@yahoo.com.

Naunyn Schmiedebergs Arch Pharmacol ; 393(10): 1809-1823, 2020 10.

Article in En | MEDLINE | ID: mdl-32399613

Subject(s)

Acetamides/therapeutic use; Cardiotonic Agents/therapeutic use; Isoproterenol/toxicity; Myocardial Infarction/metabolism; Myocardial Infarction/prevention & control; Nitric Oxide/metabolism; Acetamides/pharmacology; Animals; Cardiotonic Agents/pharmacology; Male; Myocardial Infarction/chemically induced; Myocardium/metabolism; NADPH Oxidase 2/antagonists & inhibitors; NADPH Oxidase 2/metabolism; Oxidative Stress/drug effects; Oxidative Stress/physiology; Rats; Rats, Wistar

Key words

Agomelatine; Caspase; Myocardial injury; Nitric oxide synthase

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cardiotonic Agents / Isoproterenol / Acetamides / Myocardial Infarction / Nitric Oxide Type of study: Prognostic_studies Limits: Animals Language: En Journal: Naunyn Schmiedebergs Arch Pharmacol Year: 2020 Type: Article Affiliation country: Egypt

Fulltext

XML

PubMed Links

Search on Google