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Mutation of complement factor B causing massive fluid-phase dysregulation of the alternative complement pathway can result in atypical hemolytic uremic syndrome.
Zhang, Yuzhou; Kremsdorf, Robin A; Sperati, C John; Henriksen, Kammi J; Mori, Mari; Goodfellow, Renee X; Pitcher, Gabriella R; Benson, Cindy L; Borsa, Nicolo Ghiringhelli; Taylor, Ronald P; Nester, Carla M; Smith, Richard J H.
Affiliation
  • Zhang Y; Molecular Otolaryngology and Renal Research Laboratories, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Kremsdorf RA; Department of Pediatrics, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
  • Sperati CJ; Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Henriksen KJ; Department of Pathology, The University of Chicago, Chicago, Illinois, USA.
  • Mori M; Division of Genetic and Genomic Medicine, Nationwide Children's Hospital, Columbus, Ohio, USA; Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, Ohio, USA.
  • Goodfellow RX; Molecular Otolaryngology and Renal Research Laboratories, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Pitcher GR; Molecular Otolaryngology and Renal Research Laboratories, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Benson CL; Division of Human Genetics, Department of Pediatrics, Rhode Island Hospital, Providence, Rhode Island, USA.
  • Borsa NG; Molecular Otolaryngology and Renal Research Laboratories, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Taylor RP; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
  • Nester CM; Molecular Otolaryngology and Renal Research Laboratories, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Smith RJH; Molecular Otolaryngology and Renal Research Laboratories, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA. Electronic address: richard-smith@uiowa.edu.
Kidney Int ; 98(5): 1265-1274, 2020 11.
Article in En | MEDLINE | ID: mdl-32540405
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Atypical Hemolytic Uremic Syndrome Type of study: Diagnostic_studies / Prognostic_studies Limits: Adult / Child, preschool / Female / Humans / Middle aged / Pregnancy Language: En Journal: Kidney Int Year: 2020 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Atypical Hemolytic Uremic Syndrome Type of study: Diagnostic_studies / Prognostic_studies Limits: Adult / Child, preschool / Female / Humans / Middle aged / Pregnancy Language: En Journal: Kidney Int Year: 2020 Type: Article Affiliation country: United States